NMS · Biotechnology

PTC Therapeutics, Inc. (PTCT) Stock

$76.68 -0.19% NMS: PTCT Healthcare

PTC Therapeutics, Inc. (PTCT) is a biopharmaceutical company committed to the research, development, and commercialization of innovative therapies for patients afflicted with rare genetic disorders.

Valuation

MetricValue
Price$76.68
Market Cap$6.36B
P/E Ratio-32.91
P/B Ratio-35.13
P/S Ratio7.70
EPS (TTM)$-2.54
52-Week High$90.87
52-Week Low$43.17
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE99.84%
ROA-6.51%
ROCE-3.48%
Gross Margin37.05%
Operating Margin16.54%
Net Margin-22.58%
Debt/Equity-2.19
Current Ratio2.44

Annual Financials (USD)

Metric20212022202320242025
Revenue$539.0M$699.0M$938.0M$807.0M$1.7B
Operating Profit$-374.0M$-447.0M$-440.0M$-303.0M$857.0M
Net Profit$-524.0M$-559.0M$-627.0M$-363.0M$683.0M
EPS$-7.43$-7.79$-8.37$-4.73$7.78
Op Margin-69.5%-64.0%-46.9%-37.5%49.5%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$1.9B$1.7B$1.9B$1.7B$2.9B
Total Liabilities$1.9B$2.1B$2.7B$2.8B$3.1B
Cash$190.0M$280.0M$594.0M$780.0M$985.0M
Borrowings$1.3B$1.5B$2.2B$2.5B$492.0M

Latest News

PTCT: What does Argus have to say about PTCT? Argus Research · Jul 22, 2026 uniQure Trends to Watch as Gene Therapy Bets Shift Beyond Hemgenix Zacks · Jul 17, 2026 QURE Stock Outlook Rests on AMT-130, FDA Talks, and Cash Runway Zacks · Jul 17, 2026 PTC Therapeutics to Report Second Quarter 2026 Financial Results on Thursday, July 30, 2026 PR Newswire · Jul 16, 2026 What This PTC Therapeutics Insider Sale Means as Product Revenue Hit $226 Million Motley Fool · Jul 13, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-251.0M$-357.0M$-158.0M$-108.0M$711.0M
Investing Cash Flow$134.0M$138.0M$-297.0M$-30.0M$-871.0M
Financing Cash Flow$0$-31.0M$948.0M$257.0M$232.0M
Net Cash Flow$-19.0M$99.0M$314.0M$185.0M$205.0M
Free Cash Flow$-337.0M$-509.0M$-279.0M$-182.0M$702.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.11
EV / EBITDA6.55
FCF Yield11.04%
Quick Ratio2.29
Interest Coverage5.64
Return 1Y64.02%
Return 3Y98.63%
Return 5Y86.55%

Ownership

Insiders Held7.38%
Institutions Held118.13%
Institutions Float Held127.54%
Institutional HolderSharesReport Date
Blackrock Inc.12,948,7172026-03-31
RTW Investments LP7,746,4152026-03-31
Janus Henderson Group PLC7,193,4332026-03-31
Vanguard Portfolio Management LLC4,804,5942026-03-31
State Street Corporation4,346,5192026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ACLXArcellx, Inc. $115.07 +0.02% -28.27 $6.73B 0.00%
ALKS $50.71 -3.84% 25.87 $8.45B 0.00%
ARWR $86.01 +1.61% -7397.00 $12.12B 0.00%
CRNX $83.81 -0.09% -8.57 $8.87B 0.00%
KRYS $312.57 -8.37% 42.90 $9.21B 0.00%

About PTC Therapeutics, Inc.

PTC Therapeutics, Inc. (PTCT) is a biopharmaceutical company committed to the research, development, and commercialization of innovative therapies for patients afflicted with rare genetic disorders. Its robust pipeline encompasses both commercialized therapies and a variety of experimental drug candidates, spanning all stages of development—from early research and preclinical studies to clinical trials—with a primary focus on addressing various rare disease indications. Among its commercialized products, PTC Therapeutics provides Translarna and Emflaza, offering therapeutic options for Duchenne muscular dystrophy patients in the European Economic Area and the United States. Translarna also addresses nonsense mutation Duchenne muscular dystrophy in Brazil and Russia. The company additionally commercializes Tegsedi and Waylivra for various rare conditions throughout Latin America and the Caribbean. Furthermore, in Brazil, PTC Therapeutics distributes Evrysdi as a treatment for spinal muscular atrophy (SMA) in patients aged two months and older. Leveraging its proprietary splicing platform, the company is also actively developing PTC518, a promising therapeutic candidate aimed at treating Huntington's disease. To bolster its research and development capabilities, PTC Therapeutics has established strategic collaborations, including partnerships with F. Hoffman-La Roche Ltd and Hoffman-La Roche Inc., as well as the Spinal Muscular Atrophy Foundation, focusing on advancing drug discovery and development research, particularly in regenerative medicine. Additionally, it collaborates with Akcea Therapeutics, Inc. for the commercialization of Tegsedi and Waylivra in the Latin America and Caribbean region. Established in 1998, PTC Therapeutics, Inc. maintains its corporate headquarters in South Plainfield, New Jersey.

PTC Therapeutics, Inc. (PTCT) stock trades at $76.68 with a market capitalization of $6.36B. The stock is valued at a price-to-earnings (P/E) ratio of -32.91, price-to-book of -35.13, price-to-sales of 7.70. Over the past 52 weeks the stock has ranged between $43.17 and $90.87, and currently trades 15.6% below its 52-week high.

On profitability, PTC Therapeutics, Inc. generates a return on equity (ROE) of 99.84% — well above the market average, a sign of a high-quality business, return on capital employed of -3.48%, an operating margin of 16.54%, a net profit margin of -22.58%.

Official website: www.ptcbio.com

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