NASDAQ · Medical - Diagnostics & Research

TWST (TWST) Stock

$85.47 -3.48% NASDAQ: TWST Healthcare

Valuation

MetricValue
Price$85.47
Market Cap$5.32B
P/E Ratio-38.08
P/B Ratio6.52
P/S Ratio7.53
EPS (TTM)$-1.30
52-Week High$104.12
52-Week Low$23.30
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-16.49%
ROA-12.15%
ROCE-28.75%
Gross Margin-36.07%
Operating Margin-36.07%
Net Margin-19.85%
Debt/Equity0.21
Current Ratio3.66

Annual Financials (USD)

Metric20212022202320242025
Revenue$132.0M$204.0M$245.0M$313.0M$377.0M
Operating Profit$-153.0M$-235.0M$-217.0M$-221.0M$-136.0M
Net Profit$-152.0M$-218.0M$-205.0M$-209.0M$-78.0M
EPS$-3.15$-4.04$-3.60$-3.60$-1.30
Op Margin-115.4%-115.3%-88.6%-70.6%-36.2%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$702.0M$961.0M$776.0M$614.0M$642.0M
Total Liabilities$121.0M$172.0M$153.0M$142.0M$169.0M
Cash$466.0M$379.0M$286.0M$226.0M$183.0M
Borrowings$63.0M$95.0M$94.0M$85.0M$137.0M

Latest News

Cathie Wood Dumps $39 Million Worth of AMD Stock GuruFocus.com · Jul 20, 2026 Cathie Wood Is Selling This High-Flying Stock. Is It a Buy? Motley Fool · Jul 19, 2026 Twist Bioscience to Report Fiscal 2026 Third Quarter Financial Results on Monday, August 3, 2026 Business Wire · Jul 15, 2026 Cathie Wood’s ARK Invest Doubles Down On Circle In Two Funds At Once, Trims Robinhood Again Stocktwits · Jul 15, 2026 Cathie Wood Is Loading Up on This Biotech Stock. Is It a No-Brainer Buy? Motley Fool · Jul 14, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-112.0M$-124.0M$-142.0M$-64.0M$-48.0M
Investing Cash Flow$129.0M$-335.0M$23.0M$-8.0M$-53.0M
Financing Cash Flow$9.0M$2.0M$1.0M$7.0M$15.0M
Net Cash Flow$373.0M$-87.0M$-91.0M$-60.0M$-43.0M
Free Cash Flow$-139.0M$-226.0M$-170.0M$-69.0M$-76.0M

Valuation & Return Ratios

MetricValue
PEG Ratio—
EV / EBITDA—
FCF Yield-3.09%
Quick Ratio2.42
Interest Coverage—
Return 1Y175.70%
Return 3Y281.76%
Return 5Y-21.09%

Ownership

Insiders Held1.20%
Institutions Held128.22%
Institutions Float Held129.77%
Institutional HolderSharesReport Date
Artisan Partners Limited Partnership6,367,7772026-03-31
ARK Investment Management, LLC6,342,7332026-03-31
Blackrock Inc.5,554,3622026-03-31
Edgepoint Investment Group Inc.5,382,5212026-03-31
William Blair Investment Management, LLC5,269,7182026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $313.33 +0.29% 37.72 $4.60T 0.34%
MSFTMicrosoft Corporation $499.99 +0.03% 22.95 $3.71T 0.94%
GOOGLAlphabet Inc. $354.30 -0.96% 27.68 $4.29T 0.23%
AMZNAmazon.com, Inc. $274.48 +0.82% 28.76 $2.95T 0.00%
METAMeta Platforms, Inc. $592.10 +0.37% 21.47 $1.51T 0.35%

About TWST

TWST stock trades at $85.47 with a market capitalization of $5.32B. The stock is valued at a price-to-earnings (P/E) ratio of -38.08, price-to-book of 6.52, price-to-sales of 7.53. Over the past 52 weeks the stock has ranged between $23.30 and $104.12, and currently trades 17.9% below its 52-week high.

On profitability, TWST generates a return on equity (ROE) of -16.49%, return on capital employed of -28.75%, an operating margin of -36.07%, a net profit margin of -19.85%.

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