NASDAQ · Biotechnology

Seaport Therapeutics, Inc. Common Stock (SPTX) Stock

$23.02 -2.54% NASDAQ: SPTX Healthcare

Seaport Therapeutics, Inc. is a developing biopharmaceutical enterprise currently undergoing clinical trials, focused on creating groundbreaking treatments for neuropsychiatric conditions.

Valuation

MetricValue
Price$23.02
Market Cap$1.23B
P/E Ratio-13.95
P/B Ratio2.92
P/S Ratio0.00
EPS (TTM)$-2.46
52-Week High$24.48
52-Week Low$14.85
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-57.34%
ROA-19.93%
ROCE-21.91%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.01
Current Ratio18.00

Annual Financials (USD)

Metric2025
Revenue$0
Operating Profit$-87.0M
Net Profit$-75.0M
EPS$-1.94
Op Margin

Balance Sheet (USD)

Metric2025
Total Assets$249.0M
Total Liabilities$342.0M
Cash$46.0M
Borrowings$5.0M

Latest News

PureTech Founded Entity Seaport Therapeutics Reports Positive Multiple-Ascending Dose Data from Phase 1 Proof-of-Concept Trial of GlyphAgo™ in Healthy Volunteers Business Wire · Jun 9, 2026 Seaport Therapeutics Q1 Net Loss Widens MT Newswires · Jun 8, 2026 Seaport Therapeutics Reports First Quarter 2026 Financial Results and Highlights Recent Corporate and Clinical Progress Business Wire · Jun 8, 2026 Seaport Therapeutics Reports Positive Multiple-Ascending Dose Data from Phase 1 Proof-of-Concept Trial of GlyphAgo™ in Healthy Volunteers Business Wire · Jun 8, 2026 Seaport Therapeutics to Participate in Two Upcoming Investor Conferences Business Wire · Jun 1, 2026

Cash Flow (USD)

Metric2025
Operating Cash Flow$-78.0M
Investing Cash Flow$-185.0M
Financing Cash Flow$-1.0M
Net Cash Flow$-263.0M
Free Cash Flow$-78.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.14
EV / EBITDA-12.66
FCF Yield-3.76%
Quick Ratio18.00
Interest Coverage0.00
Return 1Y
Return 3Y
Return 5Y

Ownership

Insiders Held35.06%
Institutions Held35.44%
Institutions Float Held54.56%
Institutional HolderSharesReport Date
Fidelity Securities Fund-Fidelity Blue Chip Growth Fund235,9002026-05-31
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund224,4002026-05-31
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company K6 Fund62,2962026-05-31
Fidelity Mt. Vernon Street Trust-Fidelity Series Growth Company Fund55,9002026-05-31
Fidelity Securities Fund-Fidelity Blue Chip Growth K6 Fund48,1092026-05-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $313.33 +0.29% 37.72 $4.60T 0.34%
MSFTMicrosoft Corporation $499.99 +0.03% 22.95 $3.71T 0.94%
GOOGLAlphabet Inc. $354.30 -0.96% 27.68 $4.29T 0.23%
AMZNAmazon.com, Inc. $274.48 +0.82% 28.76 $2.95T 0.00%
METAMeta Platforms, Inc. $592.10 +0.37% 21.47 $1.51T 0.35%

About Seaport Therapeutics, Inc. Common Stock

Seaport Therapeutics, Inc. is a developing biopharmaceutical enterprise currently undergoing clinical trials, focused on creating groundbreaking treatments for neuropsychiatric conditions. The company is primarily engaged in tackling disorders like depression and anxiety, utilizing its unique Glyph technology. This exclusive platform is engineered to allow for oral administration of drugs, circumventing initial metabolic processing in the liver, and thereby reducing the risk of liver enzyme elevations, hepatotoxicity, and other potential adverse reactions. Every therapeutic agent in their pipeline incorporates this advanced platform, with all research and development efforts exclusively dedicated to neuropsychiatric applications. Founded in 2024 and situated in Boston, Massachusetts, the company connects with medical professionals and influential experts across the healthcare and neuropsychiatric sectors.

Seaport Therapeutics, Inc. Common Stock is led by CEO Daphne Zohar, employs 58 people, headquartered in US, publicly traded since 2026.

Seaport Therapeutics, Inc. Common Stock (SPTX) stock trades at $23.02 with a market capitalization of $1.23B. The stock is valued at a price-to-earnings (P/E) ratio of -13.95, price-to-book of 2.92, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $14.85 and $24.48, and currently trades 6.0% below its 52-week high.

On profitability, Seaport Therapeutics, Inc. Common Stock generates a return on equity (ROE) of -57.34%, return on capital employed of -21.91%, an operating margin of 0.00%, a net profit margin of 0.00%.

Official website: www.seaporttx.com

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