NMS · Biotechnology

SPRO (SPRO) Stock

$1.18 -1.26% NMS: SPRO Healthcare

Valuation

MetricValue
Price$1.18
Market Cap$68.32M
P/E Ratio16.13
P/B Ratio2.37
P/S Ratio2.83
EPS (TTM)$0.15
52-Week High$3.22
52-Week Low$1.10
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE15.25%
ROA13.04%
ROCE0.00%
Gross Margin0.00%
Operating Margin24.66%
Net Margin27.82%
Debt/Equity0.05
Current Ratio7.44

Annual Financials (USD)

Metric20212022202320242025
Revenue$3.0M$49.0M$104.0M$48.0M$60.0M
Operating Profit$-88.0M$-42.0M$21.0M$-73.0M$0
Net Profit$-90.0M$-46.0M$23.0M$-69.0M$9.0M
EPS$-2.91$-1.23$0.43$-1.27$0.15
Op Margin-2865.5%-86.9%20.7%-152.9%-0.0%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$171.0M$125.0M$182.0M$111.0M$69.0M
Total Liabilities$83.0M$49.0M$75.0M$64.0M$10.0M
Cash$113.0M$109.0M$76.0M$53.0M$40.0M
Borrowings$7.0M$7.0M$6.0M$4.0M$3.0M

Latest News

Sector Update: Healthcare Stocks Mixed Premarket Tuesday MT Newswires · Jul 14, 2026 Spero Therapeutics Licenses Immunology Drug Candidate From Innovent, Recieves $105 Million Financing MT Newswires · Jul 14, 2026 Spero Therapeutics Lands $105 Million Royalty Financing to Advance SP001 Development (SPRO) InvestorsHub · Jul 14, 2026 Spero Therapeutics Announces $105 Million Non-Recourse Non-Dilutive Financing Backed by a Portion of Utebzi Milestones & Royalties GlobeNewswire · Jul 14, 2026 Spero Therapeutics and Innovent Biologics Announce Exclusive License for SP001 (IBI355), a Phase 2-Ready Third-Generation Anti-CD40L Antibody GlobeNewswire · Jul 14, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-64.0M$-8.0M$-33.0M$-23.0M$-13.0M
Investing Cash Flow$72.0M$34.0M$0$0$0
Financing Cash Flow$0$0$0$0$0
Net Cash Flow$27.0M$-3.0M$-33.0M$-23.0M$-13.0M
Free Cash Flow$0$-8.0M$-33.0M$-23.0M$-13.0M

Valuation & Return Ratios

MetricValue
PEG Ratio—
EV / EBITDA—
FCF Yield4.67%
Quick Ratio10.50
Interest Coverage—
Return 1Y-33.53%
Return 3Y9.60%
Return 5Y-88.53%

Ownership

Insiders Held22.46%
Institutions Held16.16%
Institutions Float Held20.84%
Institutional HolderSharesReport Date
GSK plc9,190,6062026-03-31
Pfizer Inc2,362,3482026-03-31
Vanguard Capital Management LLC1,799,8802026-03-31
Renaissance Technologies, LLC1,189,2352026-03-31
Alphabet Inc.889,9792026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABOS $2.27 -0.66% -1.17 $163.60M 0.00%
ACTU $1.09 -5.22% -2.73 $26.08M 0.00%
CGTX $0.89 +0.21% -3.94 $79.79M 0.00%
CRBP $9.11 +0.33% -1.95 $168.79M 0.00%
HURA $2.09 -2.34% -3.75 $133.10M 0.00%

About SPRO

SPRO is led by CEO Esther Rajavelu, employs 32 people, headquartered in US, publicly traded since 2017.

SPRO stock trades at $1.18 with a market capitalization of $68.32M. The stock is valued at a price-to-earnings (P/E) ratio of 16.13, price-to-book of 2.37, price-to-sales of 2.83. Over the past 52 weeks the stock has ranged between $1.10 and $3.22, and currently trades 63.4% below its 52-week high.

On profitability, SPRO generates a return on equity (ROE) of 15.25%, above the typical market average, return on capital employed of 0.00%, an operating margin of 24.66%, a net profit margin of 27.82%.

Related Healthcare Stocks

LLY Drug Manufacturers - General $1185.71 -0.52% JNJ Drug Manufacturers - General $259.24 +0.88% ABBV Drug Manufacturers - General $246.04 +0.89% UNH Medical - Healthcare Plans $407.08 +0.77% MRK Drug Manufacturers - General $128.57 +0.16% NVS Drug Manufacturers - General $158.83 -0.64% NVO Biotechnology $51.58 +1.22% TMO Medical - Diagnostics & Research $594.00 +2.41% AMGN Drug Manufacturers - General $387.64 -1.39% ABT Medical - Devices $108.03 +0.70% GILD Drug Manufacturers - General $132.73 -1.18% PFE Drug Manufacturers - General $26.74 +2.06%

Popular Stocks

Apple (AAPL)Microsoft (MSFT)NVIDIA (NVDA)Alphabet (GOOGL)Amazon (AMZN)Meta (META)Tesla (TSLA)Broadcom (AVGO)JPMorgan (JPM)Visa (V)

Screens featuring this stock

High ROE Healthcare StocksLow P/E Healthcare StocksHigh Net Margin Healthcare StocksDividend Healthcare StocksLow Debt Healthcare StocksAll stock screens
Run Stock Screener Investing Guides