NASDAQ · Biotechnology

Sionna Therapeutics, Inc. (SION) Stock

$4.90 +0.00% NASDAQ: SION Healthcare

Valuation

MetricValue
Price$4.90
Market Cap$221.24M
P/E Ratio-2.25
P/B Ratio0.83
P/S Ratio0.00
EPS (TTM)$-1.88
52-Week High$54.97
52-Week Low$4.01
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-32.94%
ROA-34.38%
ROCE-40.18%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.03
Current Ratio20.08

Annual Financials (USD)

Metric2022202320242025
Revenue$0$0$0$0
Operating Profit$-41.0M$-50.0M$-71.0M$-89.0M
Net Profit$-40.0M$-47.0M$-62.0M$-75.0M
EPS$-0.91$-1.07$-1.40$-1.88
Op Margin————

Balance Sheet (USD)

Metric2022202320242025
Total Assets$87.0M$52.0M$186.0M$326.0M
Total Liabilities$157.0M$167.0M$349.0M$19.0M
Cash$55.0M$39.0M$38.0M$58.0M
Borrowings$0$10.0M$10.0M$9.0M

Latest News

Sionna Therapeutics Insider Sold Shares Worth $3,854,281, According to a Recent SEC Filing MT Newswires · Jul 9, 2026 Sionna Therapeutics Insider Sold Shares Worth $446,862, According to a Recent SEC Filing MT Newswires · Jul 7, 2026 Assessing Sionna Therapeutics (SION) Valuation After A Mixed Period For Recent Share Price Returns Simply Wall St. · Jun 11, 2026 Sionna Therapeutics to Participate in Upcoming June 2026 Investor Conferences GlobeNewswire · May 27, 2026 Wedbush Initiates Coverage of Sionna Therapeutics (SION) Insider Monkey · May 14, 2026

Cash Flow (USD)

Metric2022202320242025
Operating Cash Flow$-36.0M$-44.0M$-53.0M$-66.0M
Investing Cash Flow$-31.0M$26.0M$-127.0M$-119.0M
Financing Cash Flow$0$0$0$0
Net Cash Flow$46.0M$-16.0M$-1.0M$21.0M
Free Cash Flow$-38.0M$-45.0M$-53.0M$-67.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.09
EV / EBITDA-1.79
FCF Yield-44.23%
Quick Ratio20.05
Interest Coverage0.00
Return 1Y136.75%
Return 3Y—
Return 5Y—

Ownership

Insiders Held6.85%
Institutions Held100.28%
Institutions Float Held107.65%
Institutional HolderSharesReport Date
RA Capital Management, L.P.9,905,0452026-03-31
TPG GP A, LLC6,494,9622026-03-31
Orbimed Advisors LLC.3,530,7022026-03-31
Viking Global Investors, L.P.3,195,1812026-03-31
Atlas Venture Life Science Advisors, LLC 2,995,6022026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABCLAbCellera Biologics Inc. $12.55 +4.37% -21.26 $3.83B 0.00%
ARDXArdelyx, Inc. $3.28 +0.31% -15.13 $810.26M 0.00%
BHVNBiohaven Ltd. $12.08 +1.26% -2.77 $1.82B 0.00%
CLDXCelldex Therapeutics, Inc. $29.89 +2.01% -7.26 $1.99B 0.00%
IMNMImmunome, Inc. $19.55 +1.24% -8.23 $1.87B 0.00%

About Sionna Therapeutics, Inc.

Sionna Therapeutics, Inc. (SION) stock trades at $4.90 with a market capitalization of $221.24M. The stock is valued at a price-to-earnings (P/E) ratio of -2.25, price-to-book of 0.83, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $4.01 and $54.97, and currently trades 91.1% below its 52-week high.

On profitability, Sionna Therapeutics, Inc. generates a return on equity (ROE) of -32.94%, return on capital employed of -40.18%, an operating margin of 0.00%, a net profit margin of 0.00%.

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