NASDAQ · Biotechnology

SION (SION) Stock

$45.38 -0.70% NASDAQ: SION Healthcare

Valuation

MetricValue
Price$45.38
Market Cap$2.05B
P/E Ratio-20.04
P/B Ratio5.54
P/S Ratio0.00
EPS (TTM)$-1.88
52-Week High$48.45
52-Week Low$13.81
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-24.43%
ROA-23.01%
ROCE-28.99%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.03
Current Ratio20.08

Annual Financials (USD)

Metric2022202320242025
Revenue$0$0$0$0
Operating Profit$-41.0M$-50.0M$-71.0M$-89.0M
Net Profit$-40.0M$-47.0M$-62.0M$-75.0M
EPS$-0.91$-1.07$-1.40$-1.88
Op Margin————

Balance Sheet (USD)

Metric2022202320242025
Total Assets$87.0M$52.0M$186.0M$326.0M
Total Liabilities$157.0M$167.0M$349.0M$19.0M
Cash$55.0M$39.0M$38.0M$58.0M
Borrowings$0$10.0M$10.0M$9.0M

Latest News

Sionna Therapeutics Insider Sold Shares Worth $3,854,281, According to a Recent SEC Filing MT Newswires · Jul 9, 2026 Sionna Therapeutics Insider Sold Shares Worth $446,862, According to a Recent SEC Filing MT Newswires · Jul 7, 2026 Assessing Sionna Therapeutics (SION) Valuation After A Mixed Period For Recent Share Price Returns Simply Wall St. · Jun 11, 2026 Sionna Therapeutics to Participate in Upcoming June 2026 Investor Conferences GlobeNewswire · May 27, 2026 Wedbush Initiates Coverage of Sionna Therapeutics (SION) Insider Monkey · May 14, 2026

Cash Flow (USD)

Metric2022202320242025
Operating Cash Flow$-36.0M$-44.0M$-53.0M$-66.0M
Investing Cash Flow$-31.0M$26.0M$-127.0M$-119.0M
Financing Cash Flow$0$0$0$0
Net Cash Flow$46.0M$-16.0M$-1.0M$21.0M
Free Cash Flow$-38.0M$-45.0M$-53.0M$-67.0M

Valuation & Return Ratios

MetricValue
PEG Ratio—
EV / EBITDA—
FCF Yield-4.24%
Quick Ratio22.60
Interest Coverage—
Return 1Y136.75%
Return 3Y—
Return 5Y—

Ownership

Insiders Held6.85%
Institutions Held100.28%
Institutions Float Held107.65%
Institutional HolderSharesReport Date
RA Capital Management, L.P.9,905,0452026-03-31
TPG GP A, LLC6,494,9622026-03-31
Orbimed Advisors LLC.3,530,7022026-03-31
Viking Global Investors, L.P.3,195,1812026-03-31
Atlas Venture Life Science Advisors, LLC 2,995,6022026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABCL $6.93 +6.13% -5.91 $2.12B 0.00%
ARDX $5.09 +0.49% 11.04 $1.26B 0.00%
BHVN $14.07 +3.19% -6.11 $2.12B 0.00%
CLDX $35.80 +0.63% -7.84 $2.38B 0.00%
IMNM $23.22 +2.83% -8.13 $2.22B 0.00%

About SION

SION stock trades at $45.38 with a market capitalization of $2.05B. The stock is valued at a price-to-earnings (P/E) ratio of -20.04, price-to-book of 5.54, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $13.81 and $48.45, and currently trades 6.3% below its 52-week high.

On profitability, SION generates a return on equity (ROE) of -24.43%, return on capital employed of -28.99%, an operating margin of 0.00%, a net profit margin of 0.00%.

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