NASDAQ · Biotechnology

Rhythm Pharmaceuticals, Inc. (RYTM) Stock

$91.98 +2.61% NASDAQ: RYTM Healthcare

Valuation

MetricValue
Price$91.98
Market Cap$6.31B
P/E Ratio-29.85
P/B Ratio29.30
P/S Ratio26.54
EPS (TTM)$-3.11
52-Week High$122.20
52-Week Low$74.50
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-80.48%
ROA-46.96%
ROCE-63.96%
Gross Margin-101.05%
Operating Margin-101.05%
Net Margin-85.59%
Debt/Equity0.02
Current Ratio4.41

Annual Financials (USD)

Metric20212022202320242025
Revenue$3.0M$24.0M$77.0M$130.0M$190.0M
Operating Profit$-170.0M$-179.0M$-184.0M$-266.0M$-192.0M
Net Profit$-70.0M$-181.0M$-185.0M$-261.0M$-197.0M
EPS$-1.37$-3.51$-3.20$-4.34$-3.11
Op Margin-5391.9%-757.9%-238.1%-204.0%-101.2%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$330.0M$382.0M$333.0M$392.0M$480.0M
Total Liabilities$45.0M$118.0M$163.0M$228.0M$210.0M
Cash$59.0M$128.0M$60.0M$89.0M$54.0M
Borrowings$3.0M$2.0M$1.0M$4.0M$4.0M

Latest News

Rhythm Pharmaceuticals Announces The New England Journal of Medicine Publication of Phase 3 TRANSCEND Trial Results in Acquired Hypothalamic Obesity GlobeNewswire · Jul 8, 2026 Is Rhythm Pharmaceuticals, Inc. (RYTM) Stock Poised for Growth After Encouraging Setmelanotide Trial Results? Insider Monkey · Jun 30, 2026 Strength Seen in Acadia (ACAD): Can Its 6.8% Jump Turn into More Strength? Zacks · Jun 29, 2026 Intel Stock and 3 Other Winners I Found Using Barchart’s High-Octane Stock Screener Barchart · Jun 22, 2026 Can Rhythm Pharmaceuticals (RYTM) ’s New Data Help Patients With a Rare Hunger Disorder? Insider Monkey · Jun 22, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-146.0M$-173.0M$-136.0M$-114.0M$-116.0M
Investing Cash Flow$-68.0M$24.0M$-6.0M$-48.0M$-138.0M
Financing Cash Flow$5.0M$83.0M$25.0M$13.0M$-20.0M
Net Cash Flow$-42.0M$68.0M$-68.0M$29.0M$-35.0M
Free Cash Flow$-151.0M$-178.0M$-136.0M$-114.0M$-117.0M

Valuation & Return Ratios

MetricValue
PEG Ratio7.47
EV / EBITDA-34.14
FCF Yield-2.36%
Quick Ratio3.20
Interest Coverage-10.86
Return 1Y0.77%
Return 3Y287.70%
Return 5Y678.58%

Ownership

Insiders Held0.77%
Institutions Held110.22%
Institutions Float Held111.07%
Institutional HolderSharesReport Date
RA Capital Management, L.P.6,666,8372026-03-31
Blackrock Inc.6,237,1512026-03-31
Baker Bros. Advisors, LP5,604,4832026-03-31
Primecap Management Company3,417,5092026-03-31
Vanguard Portfolio Management LLC3,040,7182026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $334.73 -1.67% 38.93 $4.92T 0.32%
MSFTMicrosoft Corporation $535.03 +2.38% 28.68 $3.97T 0.76%
GOOGLAlphabet Inc. $354.31 +1.73% 16.94 $4.29T 0.26%
AMZNAmazon.com, Inc. $261.46 +2.91% 19.82 $2.81T 0.00%
METAMeta Platforms, Inc. $724.11 +0.45% 27.93 $1.84T 0.28%

About Rhythm Pharmaceuticals, Inc.

Rhythm Pharmaceuticals, Inc. is led by CEO David Meeker, employs 414 people, headquartered in Boston, US, publicly traded since 2017.

Rhythm Pharmaceuticals, Inc. (RYTM) stock trades at $91.98 with a market capitalization of $6.31B. The stock is valued at a price-to-earnings (P/E) ratio of -29.85, price-to-book of 29.30, price-to-sales of 26.54. Over the past 52 weeks the stock has ranged between $74.50 and $122.20, and currently trades 24.7% below its 52-week high.

On profitability, Rhythm Pharmaceuticals, Inc. generates a return on equity (ROE) of -80.48%, return on capital employed of -63.96%, an operating margin of -101.05%, a net profit margin of -85.59%.

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