OTC · Biotechnology

Poxel S.A. (PXXLF) Stock

$0.26 +0.00% OTC: PXXLF Healthcare

Poxel S.A., a biopharmaceutical firm in the clinical stage, is dedicated to creating innovative treatments for a range of metabolic disorders, including type 2 diabetes and various liver ailments. Its flagship product, Imeglimin, is an oral drug candidate that has successfully completed Phase III clinical trials in Japan.

Valuation

MetricValue
Price$0.26
Market Cap$16.14M
P/E Ratio-0.53
P/B Ratio-0.16
P/S Ratio1.61
EPS (TTM)$-0.42
52-Week High$0.70
52-Week Low$0.25
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE33.88%
ROA-122.61%
ROCE90.73%
Gross Margin55.12%
Operating Margin-55.18%
Net Margin-275.84%
Debt/Equity-1.18
Current Ratio0.78

Annual Financials (USD)

Metric20202021202220232024
Revenue$7.0M$13.0M$1.0M$2.0M$7.0M
Operating Profit$-30.0M$-22.0M$-22.0M$-29.0M$-4.0M
Net Profit$-32.0M$-24.0M$-31.0M$-35.0M$-18.0M
EPS$-1.16$-0.83$-1.08$-0.91$-0.42
Op Margin-438.5%-167.7%-3247.8%-1452.0%-65.4%

Balance Sheet (USD)

Metric20202021202220232024
Total Assets$65.0M$55.0M$35.0M$5.0M$15.0M
Total Liabilities$38.0M$47.0M$53.0M$54.0M$74.0M
Cash$40.0M$32.0M$13.0M$2.0M$4.0M
Borrowings$24.0M$35.0M$43.0M$47.0M$71.0M

Latest News

Poxel Appoints Yves Decadt as Chief Executive Officer to Accelerate Portfolio Development and Strategic Partnerships Business Wire · Jun 10, 2026

Cash Flow (USD)

Metric20202021202220232024
Operating Cash Flow$-26.0M$-17.0M$-22.0M$-14.0M$-10.0M
Investing Cash Flow$0$0$0$0$0
Financing Cash Flow$-4.0M$-2.0M$-2.0M$-3.0M$-8.0M
Net Cash Flow$3.0M$-8.0M$-19.0M$-11.0M$1.0M
Free Cash Flow$-26.0M$-17.0M$-22.0M$-14.0M$-10.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.01
EV / EBITDA-17.76
FCF Yield0.00%
Quick Ratio0.78
Interest Coverage-0.26
Return 1Y4.00%
Return 3Y-90.00%
Return 5Y

Ownership

Insiders Held5.73%
Institutions Held4.99%
Institutions Float Held5.29%
Institutional HolderSharesReport Date
SPDR (R) Idx Shares-SPDR (R) S&P (R) International Small Cap ETF18,3782022-08-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AMHVAmerican Hemp Ventures, Inc. $0.98 +0.00% $16.47M 0.00%
BNOEFBionomics Limited $0.01 -14.89% -0.30 $8.81M 0.00%
CRPOFCeapro Inc. $0.17 -13.04% -3.74 $13.31M 0.00%
EIGRQEiger BioPharmaceuticals, Inc. $8.50 +6.25% -0.17 $12.59M 0.00%
LVCLYLiving Cell Technologies Limited $0.03 +24.39% -11.54 $11.39M 0.00%

About Poxel S.A.

Poxel S.A., a biopharmaceutical firm in the clinical stage, is dedicated to creating innovative treatments for a range of metabolic disorders, including type 2 diabetes and various liver ailments. Its flagship product, Imeglimin, is an oral drug candidate that has successfully completed Phase III clinical trials in Japan. This promising medication is also undergoing Phase III trials in the United States and Europe for the management of type 2 diabetes. Imeglimin works by enhancing pancreatic beta cell function and mitigating insulin resistance, thereby reducing key cardiovascular and metabolic risk factors such as elevated blood lipid levels and excessive body weight. Additionally, Poxel is advancing PXL770, an activator of the adenosine monophosphate-activated protein kinase (AMPK) enzyme. This compound is currently in a Phase 2a clinical trial, targeting chronic metabolic conditions, notably liver diseases like non-alcoholic steatohepatitis (NASH). The company further expands its therapeutic portfolio through strategic licensing agreements. With Enyo Pharma S.A.S., Poxel is developing PXL007 (EYP001), a synthetic non-steroidal and non-bile acid FXR agonist, which is presently in a Phase II study for treating both hepatitis B and NASH. Another collaboration, with DeuteRx LLC, involves PXL065, a mitochondrial pyruvate carrier inhibitor, now in a Phase I clinical trial for the treatment of NASH. Established in 2009, Poxel S.A. maintains its headquarters in Lyon, France.

Poxel S.A. is headquartered in FR.

Poxel S.A. (PXXLF) stock trades at $0.26 with a market capitalization of $16.14M. The stock is valued at a price-to-earnings (P/E) ratio of -0.53, price-to-book of -0.16, price-to-sales of 1.61. Over the past 52 weeks the stock has ranged between $0.25 and $0.70, and currently trades 62.9% below its 52-week high.

On profitability, Poxel S.A. generates a return on equity (ROE) of 33.88% — well above the market average, a sign of a high-quality business, return on capital employed of 90.73%, an operating margin of -55.18%, a net profit margin of -275.84%.

Official website: www.poxelpharma.com

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