NASDAQ · Biotechnology

Protagenic Therapeutics, Inc. (PTIX) Stock

$0.26 +18.18% NASDAQ: PTIX Healthcare

Protagenic Therapeutics, Inc. operates as a biopharmaceutical firm dedicated to the research and development of novel treatments designed to address neuropsychiatric and mood conditions exacerbated by stress.

Valuation

MetricValue
Price$0.26
Market Cap$470654
P/E Ratio-0.08
P/B Ratio-0.21
P/S Ratio0.00
EPS (TTM)$-3.45
52-Week High$6.20
52-Week Low$0.14
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE184.88%
ROA-241.84%
ROCE124.29%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity-1.32
Current Ratio0.34

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-4.0M$-4.0M$-5.0M$-6.0M$-6.0M
Net Profit$-5.0M$-4.0M$-5.0M$-6.0M$-5.0M
EPS$-1.24$-0.82$-1.15$-1.13$-3.45
Op Margin—————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$11.0M$8.0M$4.0M$2.0M$2.0M
Total Liabilities$1.0M$1.0M$1.0M$1.0M$7.0M
Cash$1.0M$0$1.0M$2.0M$2.0M
Borrowings$0$0$0$0$3.0M

Latest News

Protagenic Therapeutics' Lead Candidate PT00114 Attenuated Chronic Stress Responses in a Well-Established Rodent Model ACCESS Newswire · Jun 30, 2026 Protagenic Therapeutics Engages Floyd Regulatory Strategic Consulting as Regulatory Affairs Advisor and Danforth Health as Strategic Operations Partner ACCESS Newswire · May 19, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-3.0M$-2.0M$-4.0M$-4.0M$-4.0M
Investing Cash Flow$-10.0M$2.0M$5.0M$3.0M$1.0M
Financing Cash Flow$1.0M$0$0$0$4.0M
Net Cash Flow$0$0$1.0M$1.0M$4.0M
Free Cash Flow$-3.0M$-2.0M$-4.0M$-4.0M$-4.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.00
EV / EBITDA-0.18
FCF Yield-879.70%
Quick Ratio0.34
Interest Coverage-21.36
Return 1Y-92.72%
Return 3Y-99.11%
Return 5Y-99.81%

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ARTL $0.77 +1.96% -0.12 $1.80M 0.00%
CARMCarisma Therapeutics, Inc. $0.01 -5.17% 0.01 $230148 0.00%
GTBP $0.29 -4.65% -0.07 $3.12M 0.00%
INDP $1.39 -3.82% -0.06 $2.43M 0.00%
LIPOLipella Pharmaceuticals Inc. $0.07 +0.00% -0.05 $300354 0.00%

About Protagenic Therapeutics, Inc.

Protagenic Therapeutics, Inc. operates as a biopharmaceutical firm dedicated to the research and development of novel treatments designed to address neuropsychiatric and mood conditions exacerbated by stress. Foremost among its investigational products is PT00114, a laboratory-synthesized version of the teneurin carboxy-terminal associated peptide. This compound functions by emulating an innate brain signaling peptide, known for its ability to temper exaggerated stress reactions. The company's headquarters are located in New York, New York.

Protagenic Therapeutics, Inc. is headquartered in US.

Protagenic Therapeutics, Inc. (PTIX) stock trades at $0.26 with a market capitalization of $470654. The stock is valued at a price-to-earnings (P/E) ratio of -0.08, price-to-book of -0.21, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $0.14 and $6.20, and currently trades 95.8% below its 52-week high.

On profitability, Protagenic Therapeutics, Inc. generates a return on equity (ROE) of 184.88% — well above the market average, a sign of a high-quality business, return on capital employed of 124.29%, an operating margin of 0.00%, a net profit margin of 0.00%.

Official website: www.protagenic.com

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