NASDAQ · Biotechnology

Prothena Corporation plc (PRTA) Stock

$8.84 +2.67% NASDAQ: PRTA Healthcare

Valuation

MetricValue
Price$8.84
Market Cap$462.80M
P/E Ratio-9.54
P/B Ratio1.44
P/S Ratio7.60
EPS (TTM)$-1.04
52-Week High$11.80
52-Week Low$7.73
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-14.98%
ROA-14.54%
ROCE-21.57%
Gross Margin46.85%
Operating Margin-2.18%
Net Margin-80.67%
Debt/Equity0.02
Current Ratio7.68

Annual Financials (USD)

Metric20212022202320242025
Revenue$201.0M$54.0M$91.0M$135.0M$10.0M
Operating Profit$72.0M$-132.0M$-191.0M$-155.0M$-185.0M
Net Profit$67.0M$-117.0M$-147.0M$-122.0M$-244.0M
EPS$1.38$-2.47$-2.76$-2.27$-4.53
Op Margin35.9%-244.1%-209.1%-114.4%-1905.8%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$609.0M$758.0M$696.0M$547.0M$327.0M
Total Liabilities$143.0M$136.0M$135.0M$60.0M$46.0M
Cash$579.0M$710.0M$619.0M$471.0M$308.0M
Borrowings$12.0M$6.0M$12.0M$11.0M$14.0M

Latest News

PRTA Stock Rises Nearly 11% in Six Months: What's Driving It? Zacks · Jul 9, 2026 Adaptive Biotechnologies (ADPT) Moves 9.7% Higher: Will This Strength Last? Zacks · Jun 12, 2026 Prothena Corp Public Ltd Insider Bought Shares Worth $465,295, According to a Recent SEC Filing MT Newswires · Jun 5, 2026 Prothena Corp Public Ltd Insider Bought Shares Worth $471,300, According to a Recent SEC Filing MT Newswires · Jun 3, 2026 High Insider Ownership Growth Stocks To Watch In May 2026 Simply Wall St. · May 28, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$93.0M$-109.0M$-134.0M$-150.0M$-164.0M
Investing Cash Flow$-1.0M$-1.0M$-6.0M$-1.0M$0
Financing Cash Flow$16.0M$18.0M$22.0M$2.0M$0
Net Cash Flow$282.0M$132.0M$-92.0M$-149.0M$-164.0M
Free Cash Flow$92.0M$-109.0M$-137.0M$-150.0M$-164.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.05
EV / EBITDA-3.24
FCF Yield-14.64%
Quick Ratio25.05
Interest Coverage0.00
Return 1Y26.18%
Return 3Y-86.83%
Return 5Y-83.31%

Ownership

Insiders Held20.18%
Institutions Held90.77%
Institutions Float Held113.73%
Institutional HolderSharesReport Date
FMR, LLC7,551,2182026-03-31
Rubric Capital Management LP5,000,0002026-03-31
Blackrock Inc.4,644,1602026-03-31
State Street Corporation1,938,4982026-03-31
Shaw D.E. & Co., Inc.1,763,3472026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $336.64 -1.11% 38.93 $4.94T 0.32%
MSFTMicrosoft Corporation $535.07 +2.38% 28.68 $3.97T 0.76%
GOOGLAlphabet Inc. $351.66 +0.97% 16.94 $4.26T 0.26%
AMZNAmazon.com, Inc. $262.43 +3.29% 19.82 $2.82T 0.00%
METAMeta Platforms, Inc. $718.67 -0.31% 27.93 $1.83T 0.28%

About Prothena Corporation plc

Prothena Corporation plc is led by CEO Gene G. Kinney, employs 163 people, headquartered in US, publicly traded since 2012.

Prothena Corporation plc (PRTA) stock trades at $8.84 with a market capitalization of $462.80M. The stock is valued at a price-to-earnings (P/E) ratio of -9.54, price-to-book of 1.44, price-to-sales of 7.60. Over the past 52 weeks the stock has ranged between $7.73 and $11.80, and currently trades 25.1% below its 52-week high.

On profitability, Prothena Corporation plc generates a return on equity (ROE) of -14.98%, return on capital employed of -21.57%, an operating margin of -2.18%, a net profit margin of -80.67%.

Related Healthcare Stocks

LLY Eli Lilly and Company $1179.27 +0.83% JNJ Johnson & Johnson $261.44 +1.93% ABBV AbbVie Inc. $276.47 +1.49% MRK Merck & Company, Inc. Common Stock (new) $145.60 +2.26% UNH UnitedHealth Group Incorporated Common Stock (DE) $379.30 +2.25% NVS Novartis AG $143.75 +0.45% AZN AstraZeneca PLC $159.20 +0.26% TMO Thermo Fisher Scientific Inc $658.02 +0.93% AMGN Amgen Inc. $414.87 +1.82% GILD Gilead Sciences, Inc. $151.17 +2.77% ABT Abbott Laboratories $99.60 +1.13% NVO Novo Nordisk A/S $38.64 +1.20%

Popular Stocks

Apple (AAPL)Microsoft (MSFT)NVIDIA (NVDA)Alphabet (GOOGL)Amazon (AMZN)Meta (META)Tesla (TSLA)Broadcom (AVGO)JPMorgan (JPM)Visa (V)

Screens featuring this stock

High ROE Healthcare StocksLow P/E Healthcare StocksHigh Net Margin Healthcare StocksDividend Healthcare StocksLow Debt Healthcare StocksNasdaq High ROE StocksAll stock screens
Run Stock Screener Investing Guides