NASDAQ · Medical - Diagnostics & Research

Opko Health, Inc. (OPK) Stock

$1.38 +0.73% NASDAQ: OPK Healthcare

Valuation

MetricValue
Price$1.38
Market Cap$1.03B
P/E Ratio-16.37
P/B Ratio0.99
P/S Ratio1.98
EPS (TTM)$-0.30
52-Week High$1.75
52-Week Low$0.98
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-5.88%
ROA-3.98%
ROCE-8.92%
Gross Margin-36.08%
Operating Margin-36.08%
Net Margin-12.40%
Debt/Equity0.33
Current Ratio3.96

Annual Financials (USD)

Metric20212022202320242025
Revenue$1.8B$1.0B$863.0M$713.0M$607.0M
Operating Profit$19.0M$-226.0M$-157.0M$-152.0M$-219.0M
Net Profit$-30.0M$-328.0M$-189.0M$-53.0M$-226.0M
EPS$-0.05$-0.46$-0.25$-0.08$-0.30
Op Margin1.1%-22.5%-18.2%-21.3%-36.1%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$2.4B$2.2B$2.0B$2.2B$1.9B
Total Liabilities$715.0M$606.0M$622.0M$835.0M$664.0M
Cash$135.0M$153.0M$96.0M$432.0M$369.0M
Borrowings$255.0M$306.0M$327.0M$504.0M$434.0M

Latest News

Entera Reports Robust Preclinical Data for EB612 (Oral LA-PTH(1-34)) for Hypoparathyroidism and EB618 (Oral GLP-1/Glucagon) for Obesity at ENDO 2026 GlobeNewswire · Jun 16, 2026 Preclinical Data for OPKO Biologics' OPK8801001 in Acromegaly Presented at ENDO 2026 GlobeNewswire · Jun 15, 2026 Discover 3 Promising Penny Stocks With Market Caps Over $20M Simply Wall St. · Jun 9, 2026 Assessing OPKO Health (OPK) Valuation After Expanded Nicoya RAYALDEE Partnership In Greater China Simply Wall St. · Jun 7, 2026 How Investors May Respond To OPKO Health (OPK) Boosting Its Nicoya Stake And RAYALDEE Milestones Simply Wall St. · Jun 7, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$38.0M$-95.0M$-28.0M$-183.0M$-179.0M
Investing Cash Flow$4.0M$66.0M$-34.0M$327.0M$218.0M
Financing Cash Flow$0$0$0$-104.0M$-47.0M
Net Cash Flow$62.0M$18.0M$-57.0M$350.0M$-63.0M
Free Cash Flow$6.0M$-120.0M$-44.0M$-208.0M$-191.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.61
EV / EBITDA27.02
FCF Yield-11.51%
Quick Ratio2.93
Interest Coverage-3.33
Return 1Y-18.18%
Return 3Y-36.41%
Return 5Y-65.54%

Ownership

Insiders Held49.95%
Institutions Held27.01%
Institutions Float Held53.97%
Institutional HolderSharesReport Date
Rubric Capital Management LP47,791,2432026-03-31
Blackrock Inc.36,232,2232026-03-31
Vanguard Portfolio Management LLC14,769,7192026-03-31
Vanguard Capital Management LLC14,499,1642026-03-31
Geode Capital Management, LLC11,301,5012026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $336.64 -1.11% 38.93 $4.94T 0.32%
MSFTMicrosoft Corporation $535.07 +2.38% 28.68 $3.97T 0.76%
GOOGLAlphabet Inc. $351.66 +0.97% 16.94 $4.26T 0.26%
AMZNAmazon.com, Inc. $262.43 +3.29% 19.82 $2.82T 0.00%
METAMeta Platforms, Inc. $718.67 -0.31% 27.93 $1.83T 0.28%

About Opko Health, Inc.

Opko Health, Inc. is led by CEO Phillip Frost, publicly traded since 1995.

Opko Health, Inc. (OPK) stock trades at $1.38 with a market capitalization of $1.03B. The stock is valued at a price-to-earnings (P/E) ratio of -16.37, price-to-book of 0.99, price-to-sales of 1.98. Over the past 52 weeks the stock has ranged between $0.98 and $1.75, and currently trades 21.1% below its 52-week high.

On profitability, Opko Health, Inc. generates a return on equity (ROE) of -5.88%, return on capital employed of -8.92%, an operating margin of -36.08%, a net profit margin of -12.40%.

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