NASDAQ · Medical - Diagnostics & Research

OPK (OPK) Stock

$1.32 -1.12% NASDAQ: OPK Healthcare

Valuation

MetricValue
Price$1.32
Market Cap$985.15M
P/E Ratio-3.73
P/B Ratio0.67
P/S Ratio1.47
EPS (TTM)$-0.30
52-Week High$1.60
52-Week Low$0.98
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-17.82%
ROA-11.70%
ROCE-17.27%
Gross Margin-36.08%
Operating Margin-36.08%
Net Margin-36.64%
Debt/Equity0.33
Current Ratio3.96

Annual Financials (USD)

Metric20212022202320242025
Revenue$1.8B$1.0B$863.0M$713.0M$607.0M
Operating Profit$19.0M$-226.0M$-157.0M$-152.0M$-219.0M
Net Profit$-30.0M$-328.0M$-189.0M$-53.0M$-226.0M
EPS$-0.05$-0.46$-0.25$-0.08$-0.30
Op Margin1.1%-22.5%-18.2%-21.3%-36.1%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$2.4B$2.2B$2.0B$2.2B$1.9B
Total Liabilities$715.0M$606.0M$622.0M$835.0M$664.0M
Cash$135.0M$153.0M$96.0M$432.0M$369.0M
Borrowings$255.0M$306.0M$327.0M$504.0M$434.0M

Latest News

Entera Reports Robust Preclinical Data for EB612 (Oral LA-PTH(1-34)) for Hypoparathyroidism and EB618 (Oral GLP-1/Glucagon) for Obesity at ENDO 2026 GlobeNewswire · Jun 16, 2026 Preclinical Data for OPKO Biologics' OPK8801001 in Acromegaly Presented at ENDO 2026 GlobeNewswire · Jun 15, 2026 Discover 3 Promising Penny Stocks With Market Caps Over $20M Simply Wall St. · Jun 9, 2026 Assessing OPKO Health (OPK) Valuation After Expanded Nicoya RAYALDEE Partnership In Greater China Simply Wall St. · Jun 7, 2026 How Investors May Respond To OPKO Health (OPK) Boosting Its Nicoya Stake And RAYALDEE Milestones Simply Wall St. · Jun 7, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$38.0M$-95.0M$-28.0M$-183.0M$-179.0M
Investing Cash Flow$4.0M$66.0M$-34.0M$327.0M$218.0M
Financing Cash Flow$1.0M$-1.0M$0$-104.0M$-47.0M
Net Cash Flow$62.0M$18.0M$-57.0M$350.0M$-63.0M
Free Cash Flow$6.0M$-120.0M$-44.0M$-208.0M$-191.0M

Valuation & Return Ratios

MetricValue
PEG Ratio—
EV / EBITDA—
FCF Yield-20.42%
Quick Ratio3.17
Interest Coverage-2.03
Return 1Y-18.18%
Return 3Y-36.41%
Return 5Y-65.54%

Ownership

Insiders Held49.95%
Institutions Held27.01%
Institutions Float Held53.97%
Institutional HolderSharesReport Date
Rubric Capital Management LP47,791,2432026-03-31
Blackrock Inc.36,232,2232026-03-31
Vanguard Portfolio Management LLC14,769,7192026-03-31
Vanguard Capital Management LLC14,499,1642026-03-31
Geode Capital Management, LLC11,301,5012026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
CTEVClaritev Corporation $21.73 +0.56% -1.25 $370.45M 0.00%
DNTH $104.09 +2.44% -17.99 $4.35B 0.00%
LFMD $3.40 -7.61% -18.83 $164.43M 0.00%
NKTR $70.68 -0.13% -6.95 $1.38B 0.00%
OCS $11.29 +2.08% -14.61 $645.16M 0.00%

About OPK

OPK is led by CEO Phillip Frost, publicly traded since 1995.

OPK stock trades at $1.32 with a market capitalization of $985.15M. The stock is valued at a price-to-earnings (P/E) ratio of -3.73, price-to-book of 0.67, price-to-sales of 1.47. Over the past 52 weeks the stock has ranged between $0.98 and $1.60, and currently trades 17.5% below its 52-week high.

On profitability, OPK generates a return on equity (ROE) of -17.82%, return on capital employed of -17.27%, an operating margin of -36.08%, a net profit margin of -36.64%.

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