NASDAQ · Biotechnology

Milestone Pharmaceuticals Inc. (MIST) Stock

$0.77 +7.43% NASDAQ: MIST Healthcare

Valuation

MetricValue
Price$0.77
Market Cap$95.24M
P/E Ratio-1.17
P/B Ratio6.16
P/S Ratio43.02
EPS (TTM)$-0.75
52-Week High$3.06
52-Week Low$0.71
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-288.36%
ROA-46.26%
ROCE-49.27%
Gross Margin-3100.00%
Operating Margin-3100.00%
Net Margin-38.32%
Debt/Equity7.79
Current Ratio8.00

Annual Financials (USD)

Metric20212022202320242025
Revenue$15.0M$5.0M$1.0M$0$2.0M
Operating Profit$-43.0M$-60.0M$-61.0M$-42.0M$-62.0M
Net Profit$-43.0M$-58.0M$-60.0M$-42.0M$-63.0M
EPS$-1.02$-1.35$-1.39$-0.67$-0.75
Op Margin-287.1%-1192.8%-6109.8%—-4041.7%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$120.0M$74.0M$75.0M$75.0M$114.0M
Total Liabilities$7.0M$8.0M$58.0M$62.0M$72.0M
Cash$114.0M$8.0M$14.0M$25.0M$73.0M
Borrowings$1.0M$2.0M$52.0M$55.0M$58.0M

Latest News

Milestone Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) GlobeNewswire · Jul 3, 2026 Alpha Cognition Elects Robert Wills as Board Chairman MT Newswires · Jun 23, 2026 Milestone (MIST) Q1 2026 Earnings Transcript Motley Fool · Jun 1, 2026 Paroxysmal Supraventricular Tachycardia Market Analysis Report 2026-2036, Profiles of Leading Players - Medtronic, Boston Scientific, Abbott Laboratories, Milestone Pharmaceuticals, Sanofi, Pfizer GlobeNewswire · May 21, 2026 Milestone Pharmaceuticals Inc.'s (NASDAQ:MIST) Path To Profitability Simply Wall St. · May 15, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-33.0M$-52.0M$-46.0M$-29.0M$-49.0M
Investing Cash Flow$70.0M$-57.0M$5.0M$8.0M$11.0M
Financing Cash Flow$5.0M$0$-2.0M$5.0M$0
Net Cash Flow$42.0M$-107.0M$6.0M$12.0M$48.0M
Free Cash Flow$-33.0M$-53.0M$-47.0M$-29.0M$-49.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.06
EV / EBITDA-1.00
FCF Yield-60.73%
Quick Ratio7.92
Interest Coverage-7.27
Return 1Y-13.18%
Return 3Y-63.49%
Return 5Y-76.25%

Ownership

Insiders Held0.70%
Institutions Held34.69%
Institutions Float Held34.93%
Institutional HolderSharesReport Date
RTW Investments LP6,331,0012026-03-31
Propel Bio Management, LLC4,118,3212026-03-31
Two Sigma Investments, LP2,317,1762026-03-31
Goldman Sachs Group Inc2,000,0252026-03-31
Marshall Wace LLP1,944,5302026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
APLTApplied Therapeutics, Inc. $0.10 +0.00% -0.24 $14.86M 0.00%
CRBPCorbus Pharmaceuticals Holdings, Inc. $5.38 +2.09% -0.95 $99.68M 0.00%
CRDFCardiff Oncology, Inc. $1.08 +1.89% -1.87 $83.24M 0.00%
CYBNCybin Inc. $8.28 +1.22% -1.67 $413.02M 0.00%
ELTXElicio Therapeutics, Inc. $1.89 +4.42% -0.89 $36.04M 0.00%

About Milestone Pharmaceuticals Inc.

Milestone Pharmaceuticals Inc. is led by CEO Joseph G. Oliveto, publicly traded since 2019.

Milestone Pharmaceuticals Inc. (MIST) stock trades at $0.77 with a market capitalization of $95.24M. The stock is valued at a price-to-earnings (P/E) ratio of -1.17, price-to-book of 6.16, price-to-sales of 43.02. Over the past 52 weeks the stock has ranged between $0.71 and $3.06, and currently trades 74.8% below its 52-week high.

On profitability, Milestone Pharmaceuticals Inc. generates a return on equity (ROE) of -288.36%, return on capital employed of -49.27%, an operating margin of -3100.00%, a net profit margin of -38.32%.

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