NASDAQ · Biotechnology

MeiraGTx Holdings plc (MGTX) Stock

$12.31 +0.04% NASDAQ: MGTX Healthcare

MeiraGTx Holdings plc operates as a clinical-stage gene therapy company, dedicated to pioneering therapeutic solutions for individuals afflicted by serious illnesses. Its development efforts span a broad spectrum of conditions, encompassing ocular diseases like inherited forms of blindness, as well as xerostomia (dry mouth) that often follows radiation treatment for head and neck cancers.

Valuation

MetricValue
Price$12.31
Market Cap$1.14B
P/E Ratio-7.95
P/B Ratio-16.46
P/S Ratio13.67
EPS (TTM)$-1.42
52-Week High$15.35
52-Week Low$6.62
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE474.91%
ROA-49.27%
ROCE-153.50%
Gross Margin-130.86%
Operating Margin-130.86%
Net Margin-151.12%
Debt/Equity-1.51
Current Ratio0.75

Annual Financials (USD)

Metric20212022202320242025
Revenue$38.0M$16.0M$14.0M$33.0M$81.0M
Operating Profit$-73.0M$-116.0M$-137.0M$-164.0M$-106.0M
Net Profit$-80.0M$-130.0M$-84.0M$-148.0M$-114.0M
EPS$-1.80$-2.87$-1.49$-2.12$-1.42
Op Margin-193.0%-730.9%-977.8%-493.4%-130.2%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$320.0M$318.0M$327.0M$270.0M$244.0M
Total Liabilities$135.0M$200.0M$189.0M$202.0M$250.0M
Cash$138.0M$116.0M$130.0M$104.0M$66.0M
Borrowings$24.0M$92.0M$89.0M$85.0M$89.0M

Latest News

MeiraGTx (MGTX) Moves 5.5% Higher: Will This Strength Last? Zacks · Jul 8, 2026 RBC Capital Adjusts MeiraGTx Price Target to $26 From $25, Maintains Outperform Speculative Risk Rating MT Newswires · Jul 8, 2026 Top Midday Gainers MT Newswires · Jul 7, 2026 MeiraGTx Announces $400 million Strategic Investment by Oberland Capital to Support Development and Commercialization of AAV2-hAQP1 and Botaretigene Sparoparvovec (bota-vec) GlobeNewswire · Jul 7, 2026 Can MeiraGTx Holdings PLC (MGTX) Stock Double? Cash Runway Offers a Hint Insider Monkey · May 20, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-11.0M$-73.0M$-105.0M$-104.0M$-46.0M
Investing Cash Flow$-117.0M$-90.0M$14.0M$19.0M$-8.0M
Financing Cash Flow$0$-5.0M$-8.0M$-5.0M$-3.0M
Net Cash Flow$-72.0M$-22.0M$15.0M$-25.0M$-37.0M
Free Cash Flow$-66.0M$-118.0M$-126.0M$-109.0M$-50.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.35
EV / EBITDA-12.07
FCF Yield-4.39%
Quick Ratio0.75
Interest Coverage-8.83
Return 1Y42.52%
Return 3Y74.60%
Return 5Y-11.40%

Ownership

Insiders Held17.12%
Institutions Held61.14%
Institutions Float Held73.77%
Institutional HolderSharesReport Date
Sanofi12,197,7372026-03-31
Perceptive Advisors Llc10,326,1032026-03-31
Rubric Capital Management LP7,000,0002026-03-31
Johnson & Johnson6,641,0642026-03-31
Adage Capital Partners GP L.L.C.4,000,0002026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABSI $7.13 -5.69% -11.32 $1.21B 0.00%
ARVN $8.02 -3.43% -6.94 $517.14M 0.00%
ATXSAstria Therapeutics, Inc. $12.58 +0.00% -7.40 $718.13M 0.00%
AVBP $30.84 -0.55% -8.82 $1.44B 0.00%
DNA $8.07 -0.19% -1.30 $527.50M 0.00%

About MeiraGTx Holdings plc

MeiraGTx Holdings plc operates as a clinical-stage gene therapy company, dedicated to pioneering therapeutic solutions for individuals afflicted by serious illnesses. Its development efforts span a broad spectrum of conditions, encompassing ocular diseases like inherited forms of blindness, as well as xerostomia (dry mouth) that often follows radiation treatment for head and neck cancers. The company also targets various degenerative and neurodegenerative disorders, notably amyotrophic lateral sclerosis (ALS) and Parkinson's disease. Currently, several of its programs are in active clinical development, including Phase 1/2 trials for Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, radiation-induced Xerostomia, and Parkinson's. MeiraGTx is also preparing to commence a clinical program for xerostomia linked to Sjogren's syndrome and maintains preclinical initiatives for other neurodegenerative conditions. A key collaboration exists with Janssen Pharmaceuticals, Inc. to advance regulatable gene therapy treatments, leveraging MeiraGTx's proprietary riboswitch technology. Established in 2015, MeiraGTx Holdings plc is headquartered in New York, New York.

MeiraGTx Holdings plc is led by CEO Alexandria Forbes, employs 375 people, headquartered in US, publicly traded since 2018.

MeiraGTx Holdings plc (MGTX) stock trades at $12.31 with a market capitalization of $1.14B. The stock is valued at a price-to-earnings (P/E) ratio of -7.95, price-to-book of -16.46, price-to-sales of 13.67. Over the past 52 weeks the stock has ranged between $6.62 and $15.35, and currently trades 19.8% below its 52-week high.

On profitability, MeiraGTx Holdings plc generates a return on equity (ROE) of 474.91% — well above the market average, a sign of a high-quality business, return on capital employed of -153.50%, an operating margin of -130.86%, a net profit margin of -151.12%.

Official website: www.meiragtx.com

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