NASDAQ · Biotechnology

Krystal Biotech, Inc. (KRYS) Stock

$327.30 +0.84% NASDAQ: KRYS Healthcare

Valuation

MetricValue
Price$327.30
Market Cap$9.65B
P/E Ratio38.97
P/B Ratio7.00
P/S Ratio21.57
EPS (TTM)$6.84
52-Week High$382.54
52-Week Low$179.19
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE19.34%
ROA16.09%
ROCE14.41%
Gross Margin41.39%
Operating Margin41.39%
Net Margin54.82%
Debt/Equity0.01
Current Ratio9.95

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$51.0M$291.0M$389.0M
Operating Profit$-68.0M$-145.0M$-110.0M$66.0M$161.0M
Net Profit$-70.0M$-140.0M$11.0M$89.0M$205.0M
EPS$-3.13$-5.49$0.39$3.00$6.84
Op Margin——-216.4%22.6%41.5%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$626.0M$558.0M$818.0M$1.1B$1.3B
Total Liabilities$33.0M$36.0M$40.0M$109.0M$114.0M
Cash$341.0M$162.0M$358.0M$345.0M$496.0M
Borrowings$8.0M$9.0M$8.0M$7.0M$9.0M

Latest News

These Are 5 Of The Best Stocks To Buy Or Watch Now Investor's Business Daily · Jul 10, 2026 3 Soaring Stocks That May Have More Upside Ahead Motley Fool · Jul 7, 2026 Krystal Biotech (KRYS) Soars 3.4%: Is Further Upside Left in the Stock? Zacks · Jun 29, 2026 Entertainment Stocks Madison Square Garden, Sphere Rally To New Highs Investor's Business Daily · Jun 26, 2026 The Brown Capital Management Small Company Fund Bets on Krystal Biotech (KRYS) for Its Resilient Revenue Stream Insider Monkey · Jun 24, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-48.0M$-101.0M$-89.0M$123.0M$201.0M
Investing Cash Flow$-295.0M$-167.0M$71.0M$-168.0M$-70.0M
Financing Cash Flow$-8.0M$-1.0M$-1.0M$-5.0M$-14.0M
Net Cash Flow$73.0M$-179.0M$196.0M$-13.0M$151.0M
Free Cash Flow$-116.0M$-154.0M$-101.0M$119.0M$189.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.63
EV / EBITDA41.58
FCF Yield2.71%
Quick Ratio7.96
Interest Coverage0.00
Return 1Y80.99%
Return 3Y184.03%
Return 5Y528.72%

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABEOAbeona Therapeutics Inc. $4.96 -2.36% -4.43 $282.70M 0.00%
MGTXMeiraGTx Holdings plc $10.50 -2.96% 17.43 $972.40M 0.00%
RCKTRocket Pharmaceuticals, Inc. $2.63 +3.75% -16.00 $287.18M 0.00%
RGNXREGENXBIO Inc. $8.09 +6.52% -1.96 $418.23M 0.00%
SANASana Biotechnology, Inc. $2.79 +2.57% -3.80 $776.43M 0.00%

About Krystal Biotech, Inc.

Krystal Biotech, Inc. is led by CEO Krish S. Krishnan, employs 295 people, headquartered in Pittsburgh, US, publicly traded since 2017.

Krystal Biotech, Inc. (KRYS) stock trades at $327.30 with a market capitalization of $9.65B. The stock is valued at a price-to-earnings (P/E) ratio of 38.97, price-to-book of 7.00, price-to-sales of 21.57. Over the past 52 weeks the stock has ranged between $179.19 and $382.54, and currently trades 14.4% below its 52-week high.

On profitability, Krystal Biotech, Inc. generates a return on equity (ROE) of 19.34%, above the typical market average, return on capital employed of 14.41%, an operating margin of 41.39%, a net profit margin of 54.82%.

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