OTC · Drug Manufacturers - General

Kyowa Kirin Co., Ltd. (KYKOF) Stock

$14.43 +0.00% OTC: KYKOF Healthcare

Kyowa Kirin Co., Ltd. is a global pharmaceutical company engaged in the development, manufacturing, and commercialization of medicines, with a primary focus on therapeutic areas including oncology, nephrology, central nervous system disorders, and immunological conditions.

Valuation

MetricValue
Price$14.43
Market Cap$7.55B
P/E Ratio18.86
P/B Ratio1.54
P/S Ratio2.69
EPS (TTM)$0.77
52-Week High$18.00
52-Week Low$12.42
Dividend Yield3.12%

Financials & Margins

MetricValue
ROE8.39%
ROA6.83%
ROCE11.92%
Gross Margin73.30%
Operating Margin21.54%
Net Margin14.28%
Debt/Equity0.02
Current Ratio3.18

Annual Financials (USD)

Metric20212022202320242025
Revenue$352.2B$398.4B$442.2B$495.6B$497.3B
Operating Profit$61.2B$82.4B$86.4B$91.9B$102.4B
Net Profit$52.3B$53.6B$81.2B$59.9B$67.1B
EPS$97.39$99.66$151.01$113.06$128.18
Op Margin17.4%20.7%19.6%18.5%20.6%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$921.9B$939.9B$1.03T$1.07T$1.11T
Total Liabilities$184.7B$177.1B$189.5B$216.6B$214.7B
Cash$335.1B$339.2B$403.1B$244.7B$219.0B
Borrowings$22.5B$21.6B$19.3B$138.0M$26.2B

Latest News

European Commission Approves Crysvita® (burosumab) for Infants with X-linked Hypophosphataemia in the European Union Business Wire · Jul 21, 2026 Systemic Lupus Erythematosus Market at a Turning Point as 6 Late-Stage Emerging Therapies Set to Redefine Treatment Landscape | DelveInsight PR Newswire · Jul 9, 2026 Lilly and Regeneron amongst first incumbents to FDA’s fast-track facility scheme Pharmaceutical Technology · Jun 30, 2026 FDA Selects Kyowa Kirin for PreCheck Pilot Program to Accelerate Manufacturing Timelines and Enhance Supply Chain Resilience GlobeNewswire · Jun 30, 2026 New Analyses Advance Understanding of Long-Term Survival Outcomes with Mogamulizumab in Mycosis Fungoides and Sézary Syndrome GlobeNewswire · Jun 30, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$86.5B$48.7B$115.6B$67.9B$100.1B
Investing Cash Flow$-31.1B$-45.9B$-53.2B$-247.7B$-133.8B
Financing Cash Flow$-4.3B$-7.0M$132.0M$-44.2B$-6.0B
Net Cash Flow$48.1B$4.1B$63.9B$-158.4B$-25.1B
Free Cash Flow$66.8B$20.0B$82.7B$-37.4B$59.0B

Valuation & Return Ratios

MetricValue
PEG Ratio0.44
EV / EBITDA9.05
FCF Yield7.84%
Quick Ratio2.73
Interest Coverage19.05
Return 1Y-2.20%
Return 3Y-22.43%
Return 5Y

Ownership

Insiders Held55.00%
Institutions Held19.25%
Institutions Float Held42.77%
Institutional HolderSharesReport Date
Pacer Advisors, Inc.1,9082026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ESAIYEisai Co., Ltd. $6.93 +0.73% 33.27 $7.82B 2.89%
ESALFEisai Co., Ltd. $26.18 +0.00% 33.27 $7.39B 3.74%
GIFLFGrifols, S.A. $10.25 +0.00% 15.97 $6.98B 0.88%
GIFOFGrifols, S.A. $8.85 +0.00% 15.97 $8.70B 1.24%
MSMKFMatsukiyoCocokara & Co. $14.88 +0.00% 17.37 $5.85B 2.28%

About Kyowa Kirin Co., Ltd.

Kyowa Kirin Co., Ltd. is a global pharmaceutical company engaged in the development, manufacturing, and commercialization of medicines, with a primary focus on therapeutic areas including oncology, nephrology, central nervous system disorders, and immunological conditions. The company's extensive pharmaceutical portfolio encompasses solutions across its core therapeutic areas. Within oncology, key products include ABSTRAL, a sublingual fentanyl formulation for breakthrough cancer pain management, and LEUNASE, utilized for acute lymphoblastic leukemia. They also offer GRAN, a human colony-stimulating factor, and the G-LASTA/Peglasta/Neulasta range, developed to address chemotherapy-induced febrile neutropenia. Pain management also includes PecFent, a nasal spray, while SANCUSO is available to treat chemotherapy-related nausea and vomiting. POTELIGEO, a humanized monoclonal antibody, targets the CC chemokine receptor 4. In nephrology, Kyowa Kirin's offerings feature CONIEL, a calcium channel blocker for hypertension and angina pectoris, along with erythropoiesis stimulating agents like ESPO and NESP. Treatments for secondary hyperparathyroidism include REGPARA and the oral calcimimetics agent ORKEDIA. Crysvita, a recombinant human monoclonal IgG1 antibody, is specifically designed to target fibroblast growth factor 23. For central nervous system disorders, Nouriast/Nourianz acts as an adenosine receptor antagonist in Parkinson's disease. Immunological conditions and allergies are addressed by ALLELOCK, an antihistamine, and LUMICEF, a biological therapy for moderate to severe plaque psoriasis. Additional products include Moventig, a mu-opioid receptor antagonist for opioid-induced constipation, and Romiplate/Nplate, a genetically recombinant protein that stimulates platelet production via thrombopoietin receptors. Beyond its existing portfolio, Kyowa Kirin is actively expanding its pipeline through strategic collaborations. A notable partnership with Amgen Inc. involves the co-development and future commercialization of KHK4083. This Phase 3-ready asset is an anti-OX40 fully human monoclonal antibody intended for the treatment of atopic dermatitis. Tracing its origins back to its incorporation in 1949, the company adopted its current name, Kyowa Kirin Co., Ltd., in June 2019, previously operating as Kyowa Hakko Kirin Co., Ltd. It maintains its headquarters in Tokyo, Japan, and operates as a subsidiary of Kirin Holdings Company, Limited.

Kyowa Kirin Co., Ltd. is headquartered in JP.

Kyowa Kirin Co., Ltd. (KYKOF) stock trades at $14.43 with a market capitalization of $7.55B. The stock is valued at a price-to-earnings (P/E) ratio of 18.86, price-to-book of 1.54, price-to-sales of 2.69. Over the past 52 weeks the stock has ranged between $12.42 and $18.00, and currently trades 19.8% below its 52-week high. It pays a dividend yielding 3.12%.

On profitability, Kyowa Kirin Co., Ltd. generates a return on equity (ROE) of 8.39%, return on capital employed of 11.92%, an operating margin of 21.54%, a net profit margin of 14.28%.

Official website: www.kyowakirin.co.jp

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