NASDAQ · Biotechnology

Opus Genetics, Inc. (IRD) Stock

$3.32 +7.63% NASDAQ: IRD Healthcare

Opus Genetics, Inc. is a clinical-stage biopharmaceutical company focused on ophthalmology.

Valuation

MetricValue
Price$3.32
Market Cap$273.71M
P/E Ratio-2.35
P/B Ratio-58.39
P/S Ratio21.22
EPS (TTM)$-0.80
52-Week High$5.81
52-Week Low$1.04
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-333.33%
ROA-160.11%
ROCE-74.91%
Gross Margin-278.57%
Operating Margin-278.57%
Net Margin-892.36%
Debt/Equity-0.57
Current Ratio6.25

Annual Financials (USD)

Metric20212022202320242025
Revenue$1.0M$40.0M$19.0M$11.0M$14.0M
Operating Profit$-23.0M$18.0M$-11.0M$-62.0M$-39.0M
Net Profit$-57.0M$18.0M$-10.0M$-58.0M$-50.0M
EPS$-3.82$0.87$-0.46$-2.15$-0.80
Op Margin-3854.8%45.7%-55.5%-564.7%-271.9%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$26.0M$49.0M$54.0M$37.0M$50.0M
Total Liabilities$4.0M$3.0M$4.0M$30.0M$35.0M
Cash$25.0M$43.0M$51.0M$30.0M$45.0M
Borrowings$1.0M$0$0$0$0

Latest News

Opus Genetics Provides BEST1 Program Update with Detailed Timeline for OPGx-BEST1 Results GlobeNewswire · Jul 9, 2026 Opus Genetics Unlocks Key Milestone With US FDA Alignment on OPGx-LCA5 Phase 3, Wedbush Says MT Newswires · Jul 6, 2026 Sector Update: Healthcare Stocks Mixed Premarket Monday MT Newswires · Jul 6, 2026 Opus Genetics Announces FDA Alignment on Phase 3 Registrational Trial Design for OPGx-LCA5 in LCA5-Associated Inherited Retinal Disease GlobeNewswire · Jul 6, 2026 RBC Capital Bullish On Opus Genetics (IRD) Amid Limited Competition And De-Risked Setup Insider Monkey · Jul 5, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-19.0M$14.0M$-1.0M$-26.0M$-35.0M
Investing Cash Flow$0$0$0$1.0M$0
Financing Cash Flow$-1.0M$0$0$0$0
Net Cash Flow$8.0M$18.0M$8.0M$-20.0M$15.0M
Free Cash Flow$-19.0M$14.0M$-1.0M$-26.0M$-35.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.17
EV / EBITDA-2.32
FCF Yield-12.79%
Quick Ratio6.25
Interest Coverage-39.00
Return 1Y143.33%
Return 3Y-25.70%
Return 5Y-10.33%

Ownership

Insiders Held11.06%
Institutions Held55.14%
Institutions Float Held62.00%
Institutional HolderSharesReport Date
Caligan Partners, LP6,075,0282026-03-31
Adage Capital Partners GP L.L.C.6,029,7752026-03-31
Bios Capital Management, LP 3,683,4292026-03-31
Balyasny Asset Management LP2,718,0292026-03-31
Millennium Management Llc2,630,4322026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABOS $2.27 -0.66% -1.17 $163.60M 0.00%
AGENAgenus Inc. $6.06 +1.34% 3.46 $252.35M 0.00%
ALEC $1.52 +0.33% -1.58 $168.20M 0.00%
CGTX $0.89 +0.21% -3.94 $79.79M 0.00%
HURA $2.09 -2.34% -3.75 $133.10M 0.00%

About Opus Genetics, Inc.

Opus Genetics, Inc. is a clinical-stage biopharmaceutical company focused on ophthalmology. The company is dedicated to discovering and commercializing innovative therapies to address significant unmet medical needs in patients suffering from refractive and retinal eye disorders. Its portfolio includes Phentolamine Ophthalmic Solution, currently used to reverse pharmacologically induced mydriasis (pupil dilation). This solution is also advancing through Phase III clinical trials for the treatment of presbyopia and impaired vision in dim light or at night. A leading candidate in its retinal pipeline is APX3330, a small-molecule inhibitor targeting the reduction oxidation effector factor-1 protein. APX3330 has successfully completed Phase II clinical trials for diabetic retinopathy. Furthermore, Opus Genetics is developing APX2009 and APX2014, two preclinical product candidates also aimed at various retinal indications. Originally founded in 2018 as Ocuphire Pharma, Inc., the company maintains its headquarters in Farmington Hills, Michigan.

Opus Genetics, Inc. is led by CEO George Magrath, employs 18 people, headquartered in US, publicly traded since 2015.

Opus Genetics, Inc. (IRD) stock trades at $3.32 with a market capitalization of $273.71M. The stock is valued at a price-to-earnings (P/E) ratio of -2.35, price-to-book of -58.39, price-to-sales of 21.22. Over the past 52 weeks the stock has ranged between $1.04 and $5.81, and currently trades 42.9% below its 52-week high.

On profitability, Opus Genetics, Inc. generates a return on equity (ROE) of -333.33%, return on capital employed of -74.91%, an operating margin of -278.57%, a net profit margin of -892.36%.

Official website: opusgtx.com

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