OTC · Biotechnology

Innate Pharma S.A. (IPHYF) Stock

$1.65 +0.00% OTC: IPHYF Healthcare

Innate Pharma S.A., a biotechnology firm based in Marseille, France, operates globally, focusing on the discovery, advancement, and commercialization of innovative antibody-based therapies, primarily targeting various oncological conditions. The company's clinical pipeline includes several promising candidates: Lacutamab (IPH4102): An anti-KIR3DL2 antibody currently undergoing Phase II clinical evaluation for cutaneous T-cell and peripheral T-cell lymphoma, as well as refractory Sézary syndrome.

Valuation

MetricValue
Price$1.65
Market Cap$154.94M
P/E Ratio-2.84
P/B Ratio-6.58
P/S Ratio52.63
EPS (TTM)$-0.55
52-Week High$2.25
52-Week Low$1.31
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE593.93%
ROA-78.41%
ROCE-220.01%
Gross Margin100.00%
Operating Margin-1766.67%
Net Margin-1633.33%
Debt/Equity-1.04
Current Ratio1.27

Annual Financials (USD)

Metric20212022202320242025
Revenue$12.0M$50.0M$62.0M$13.0M$3.0M
Operating Profit$-48.0M$-57.0M$-13.0M$-52.0M$-53.0M
Net Profit$-53.0M$-58.0M$-8.0M$-49.0M$-49.0M
EPS$-0.57$-0.73$-0.09$-0.61$-0.55
Op Margin-394.9%-115.7%-20.6%-408.6%-1917.7%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$267.0M$208.0M$175.0M$111.0M$63.0M
Total Liabilities$160.0M$154.0M$132.0M$102.0M$84.0M
Cash$104.0M$84.0M$71.0M$66.0M$28.0M
Borrowings$44.0M$42.0M$40.0M$31.0M$23.0M

Latest News

Innate Pharma to Participate in a Bladder Cancer Panel at the BTIG Virtual Biotechnology Conference Business Wire · Jul 23, 2026 Innate Pharma Closes Enrollment in Phase 1 Advanced Solid Tumors Study MT Newswires · Jul 21, 2026 Innate Pharma Announces Completion of Enrollment in Phase 1 Dose Escalation Study of IPH4502, a Novel Nectin-4 Exatecan Antibody-drug Conjugate (ADC) Business Wire · Jul 21, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-58.0M$-19.0M$-33.0M$-7.0M$-53.0M
Investing Cash Flow$-2.0M$1.0M$18.0M$9.0M$7.0M
Financing Cash Flow$0$0$0$3.0M$-7.0M
Net Cash Flow$-33.0M$-20.0M$-14.0M$-4.0M$-30.0M
Free Cash Flow$-60.0M$-20.0M$-35.0M$-7.0M$-53.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.29
EV / EBITDA-2.52
FCF Yield-36.06%
Quick Ratio1.27
Interest Coverage-18.38
Return 1Y25.95%
Return 3Y-44.82%
Return 5Y-47.62%

Ownership

Insiders Held20.77%
Institutions Held10.06%
Institutions Float Held12.69%
Institutional HolderSharesReport Date
Dimensional ETF Trust-Dimensional International Small Cap ETF23,2772026-01-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $313.33 +0.29% 37.72 $4.60T 0.34%
MSFTMicrosoft Corporation $499.99 +0.03% 22.95 $3.71T 0.94%
GOOGLAlphabet Inc. $354.30 -0.96% 27.68 $4.29T 0.23%
AMZNAmazon.com, Inc. $274.48 +0.82% 28.76 $2.95T 0.00%
METAMeta Platforms, Inc. $592.10 +0.37% 21.47 $1.51T 0.35%

About Innate Pharma S.A.

Innate Pharma S.A., a biotechnology firm based in Marseille, France, operates globally, focusing on the discovery, advancement, and commercialization of innovative antibody-based therapies, primarily targeting various oncological conditions. The company's clinical pipeline includes several promising candidates: Lacutamab (IPH4102): An anti-KIR3DL2 antibody currently undergoing Phase II clinical evaluation for cutaneous T-cell and peripheral T-cell lymphoma, as well as refractory Sézary syndrome. Monalizumab: An immune checkpoint inhibitor that has progressed to Phase III clinical trials, being investigated for its potential in treating advanced solid tumors, notably colorectal, lung, and head and neck cancers. Avdoralimab (IPH5401): A monoclonal antibody designed to block C5a binding to C5aR1. This compound is in Phase II clinical assessment for a range of inflammatory conditions, including COVID-19, bullous pemphigoid, and chronic spontaneous urticaria. IPH5201: A blocking antibody in Phase I trials, aimed at the CD39 immunosuppressive pathway. IPH5301: An anti-CD73 antibody targeting the immunosuppressive adenosine pathway to enhance anti-tumor immunity. IPH6101: An NKp46-based NK cell engager, intended for the development and assessment of up to two bispecific NK cell engagers. Beyond its clinical programs, Innate Pharma maintains an active preclinical research effort, featuring candidates such as IPH43 (an anti-MICA/B antibody-drug conjugate), an Anti-Siglec-9 antibody program, IPH65 (a proprietary tetraspecific antibody), IPH25 (a checkpoint inhibitor), and the IPH62 and IPH64 programs. To support its development and market reach, Innate Pharma has established strategic alliances and licensing agreements with major pharmaceutical companies, including AstraZeneca, Novo Nordisk A/S, Sanofi, and Orega Biotech. Additionally, it holds a co-development and license agreement with MedImmune Limited. The company was founded in 1999 and continues to operate from its headquarters in Marseille, France.

Innate Pharma S.A. is headquartered in FR.

Innate Pharma S.A. (IPHYF) stock trades at $1.65 with a market capitalization of $154.94M. The stock is valued at a price-to-earnings (P/E) ratio of -2.84, price-to-book of -6.58, price-to-sales of 52.63. Over the past 52 weeks the stock has ranged between $1.31 and $2.25, and currently trades 26.7% below its 52-week high.

On profitability, Innate Pharma S.A. generates a return on equity (ROE) of 593.93% — well above the market average, a sign of a high-quality business, return on capital employed of -220.01%, an operating margin of -1766.67%, a net profit margin of -1633.33%.

Official website: www.innate-pharma.com

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