NASDAQ · Biotechnology

Innate Pharma S.A. (IPHA) Stock

$1.79 +0.14% NASDAQ: IPHA Healthcare

Innate Pharma S.A. is a biotechnology firm, founded in 1999 and headquartered in Marseille, France, that specializes in the discovery, development, and market introduction of therapeutic antibodies.

Valuation

MetricValue
Price$1.79
Market Cap$168.32M
P/E Ratio-2.89
P/B Ratio-6.70
P/S Ratio53.57
EPS (TTM)$-0.53
52-Week High$2.63
52-Week Low$1.17
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE593.93%
ROA-78.41%
ROCE-220.01%
Gross Margin100.00%
Operating Margin-1766.67%
Net Margin-1633.33%
Debt/Equity-1.04
Current Ratio1.27

Annual Financials (USD)

Metric20212022202320242025
Revenue$12.0M$58.0M$52.0M$13.0M$3.0M
Operating Profit$-48.0M$-57.0M$-13.0M$-52.0M$-53.0M
Net Profit$-53.0M$-58.0M$-8.0M$-49.0M$-49.0M
EPS$-0.57$-0.73$-0.09$-0.61$-0.53
Op Margin-394.9%-99.6%-24.4%-408.6%-1916.9%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$267.0M$208.0M$175.0M$111.0M$63.0M
Total Liabilities$160.0M$154.0M$132.0M$102.0M$84.0M
Cash$104.0M$84.0M$71.0M$66.0M$28.0M
Borrowings$44.0M$42.0M$40.0M$31.0M$23.0M

Latest News

Innate Pharma Q1 Earnings Call Highlights MarketBeat · May 13, 2026 Peripheral T-Cell Lymphoma Market to Witness Significant Expansion at a CAGR of 7% During the Forecast Period (2026–2036) Amid Advancing Treatment Landscape | DelveInsight GlobeNewswire · Apr 27, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-58.0M$-19.0M$-33.0M$-7.0M$-33.0M
Investing Cash Flow$-2.0M$1.0M$18.0M$9.0M$18.0M
Financing Cash Flow$0$0$0$3.0M$0
Net Cash Flow$-33.0M$-20.0M$-14.0M$-4.0M$-14.0M
Free Cash Flow$-60.0M$-20.0M$-35.0M$-7.0M$-35.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.29
EV / EBITDA-2.57
FCF Yield-35.43%
Quick Ratio1.27
Interest Coverage-18.38
Return 1Y1.69%
Return 3Y-44.27%
Return 5Y-43.57%

Ownership

Insiders Held1.67%
Institutions Held0.45%
Institutions Float Held0.46%
Institutional HolderSharesReport Date
Lion Point Capital, LP81,1512026-03-31
Jane Street Group, LLC43,3652026-03-31
Morgan Stanley43,5242026-03-31
Rhumbline Advisers4,7342026-03-31
Millennium Management Llc10,0642026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
APLTApplied Therapeutics, Inc. $0.10 +0.00% -0.24 $14.86M 0.00%
CGEN $2.27 -4.83% 7.21 $214.16M 0.00%
CRBP $9.11 +0.33% -1.95 $168.79M 0.00%
CRDF $0.81 -2.98% -2.58 $53.22M 0.00%
CYBNCybin Inc. $8.28 +1.22% -1.67 $413.02M 0.00%

About Innate Pharma S.A.

Innate Pharma S.A. is a biotechnology firm, founded in 1999 and headquartered in Marseille, France, that specializes in the discovery, development, and market introduction of therapeutic antibodies. The company primarily targets oncology indications across France and internationally, with some programs also addressing inflammatory diseases and viral infections. Its clinical-stage pipeline features several key assets: Lacutamab (IPH4102): An anti-KIR3DL2 antibody undergoing Phase II trials for cutaneous T-cell and peripheral T-cell lymphoma, and also for refractory Sézary syndrome. Monalizumab: An immune checkpoint inhibitor currently in Phase III clinical trials for various advanced solid tumors, including colorectal, lung, and head and neck cancers. Avdoralimab (IPH5401): A monoclonal antibody designed to block C5a binding to C5aR1, which is in Phase II development for COVID-19, bullous pemphigoid, chronic spontaneous urticaria, and other inflammatory conditions. IPH5201: A blocking antibody in Phase I trials, focused on the CD39 immunosuppressive pathway. IPH5301: An anti-CD73 antibody developed to enhance anti-tumor immunity by targeting the immunosuppressive adenosine pathway. IPH6101: An NKp46-based NK cell engager being evaluated for the generation of up to two bispecific NK cell engagers. Innate Pharma also maintains an active preclinical pipeline, including IPH43 (an anti-MICA/B antibody drug conjugate), an Anti-Siglec-9 antibody program, IPH65 (a proprietary tetraspecific antibody), IPH25 (a checkpoint inhibitor), and the IPH62 and IPH64 programs. The company has established strategic licensing and collaboration agreements with major industry players such as AstraZeneca, Novo Nordisk A/S, Sanofi, and Orega Biotech, alongside a co-development and license agreement with MedImmune Limited.

Innate Pharma S.A. is headquartered in FR.

Innate Pharma S.A. (IPHA) stock trades at $1.79 with a market capitalization of $168.32M. The stock is valued at a price-to-earnings (P/E) ratio of -2.89, price-to-book of -6.70, price-to-sales of 53.57. Over the past 52 weeks the stock has ranged between $1.17 and $2.63, and currently trades 31.9% below its 52-week high.

On profitability, Innate Pharma S.A. generates a return on equity (ROE) of 593.93% — well above the market average, a sign of a high-quality business, return on capital employed of -220.01%, an operating margin of -1766.67%, a net profit margin of -1633.33%.

Official website: www.innate-pharma.com

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