NYSE · Biotechnology

Gelesis Holdings, Inc. (GLS) Stock

$0.16 +0.00% NYSE: GLS Healthcare

Gelesis Holdings Inc. is a biopharmaceutical company actively marketing products, dedicated to creating biomimetic solutions that target the underlying causes of obesity and chronic gastrointestinal conditions.

Valuation

MetricValue
Price$0.16
Market Cap$11.63M
P/E Ratio-0.20
P/B Ratio-0.44
P/S Ratio0.45
EPS (TTM)$-0.79
52-Week High$5.67
52-Week Low$0.01
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE31.43%
ROA-53.99%
ROCE-231.39%
Gross Margin-6.95%
Operating Margin-472.72%
Net Margin-216.48%
Debt/Equity-2.48
Current Ratio0.46

Annual Financials (USD)

Metric202020212022
Revenue$11.0M$26.0M
Operating Profit$-85.0M$-122.0M
Net Profit$-93.0M$-56.0M
EPS$-16.34$-0.79
Op Margin-759.7%-472.7%

Balance Sheet (USD)

Metric202020212022
Total Assets$0$146.0M$103.0M
Total Liabilities$0$146.0M$103.0M
Cash$0$28.0M$7.0M
Borrowings$0$66.0M$62.0M

Latest News

Greenwich LifeSciences Announces Approval to Expand FLAMINGO-01 into the United Kingdom GlobeNewswire · Jul 22, 2026 Greenwich LifeSciences Provides Clinical Updates on FLAMINGO-01 GlobeNewswire · Jul 20, 2026 Greenwich LifeSciences Says EU Regulator Approves Combination of HLA Patients in Phase 3 Trial MT Newswires · Jul 16, 2026 Greenwich LifeSciences Announces European Approval for Combining Both HLA Populations in FLAMINGO-01 GlobeNewswire · Jul 16, 2026 Sector Update: Healthcare Stocks Mixed Pre-Bell Thursday MT Newswires · Jul 9, 2026

Cash Flow (USD)

Metric202020212022
Operating Cash Flow$-55.0M$-78.0M
Investing Cash Flow$-16.0M$-18.0M
Financing Cash Flow$33.0M$66.0M
Net Cash Flow$-20.0M$-21.0M
Free Cash Flow$0$-75.0M$-87.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.01
EV / EBITDA-0.55
FCF Yield-746.72%
Quick Ratio0.33
Interest Coverage-122.91
Return 1Y
Return 3Y
Return 5Y

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AMTIApplied Molecular Transport Inc. $0.26 -3.13% -0.08 $11.01M 0.00%
AXLAAxcella Health Inc. $4.58 +0.00% -3.61 $12.50M 0.00%
CYCCCyclacel Pharmaceuticals, Inc. $6.37 -5.98% -26.54 $10.61M 0.00%
HURA $2.09 -2.34% -3.75 $133.10M 0.00%
KRRO $10.72 +0.75% -0.80 $106.70M 0.00%

About Gelesis Holdings, Inc.

Gelesis Holdings Inc. is a biopharmaceutical company actively marketing products, dedicated to creating biomimetic solutions that target the underlying causes of obesity and chronic gastrointestinal conditions. Among its key offerings is PLENITY, an oral therapeutic designed for weight management that is non-stimulant and does not enter the bloodstream. The company also provides an additional product for individuals who are overweight or obese, and its robust pipeline features potential treatments for non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, type 2 diabetes, and GS500 for Functional Constipation. Established in 2006, Gelesis Holdings Inc. operates from its headquarters in Boston, Massachusetts.

Gelesis Holdings, Inc. is headquartered in US.

Gelesis Holdings, Inc. (GLS) stock trades at $0.16 with a market capitalization of $11.63M. The stock is valued at a price-to-earnings (P/E) ratio of -0.20, price-to-book of -0.44, price-to-sales of 0.45. Over the past 52 weeks the stock has ranged between $0.01 and $5.67, and currently trades 97.2% below its 52-week high.

On profitability, Gelesis Holdings, Inc. generates a return on equity (ROE) of 31.43% — well above the market average, a sign of a high-quality business, return on capital employed of -231.39%, an operating margin of -472.72%, a net profit margin of -216.48%.

Official website: www.gelesis.com

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