NASDAQ · Biotechnology

Exelixis, Inc. (EXEL) Stock

$55.96 +0.27% NASDAQ: EXEL Healthcare

Exelixis, Inc. operates as a biotechnology firm dedicated to combating cancer, primarily focusing on the identification, advancement, and marketing of novel oncological treatments within the United States.

Valuation

MetricValue
Price$55.96
Market Cap$14.07B
P/E Ratio16.38
P/B Ratio6.01
P/S Ratio5.23
EPS (TTM)$2.78
52-Week High$57.40
52-Week Low$33.76
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE40.99%
ROA22.03%
ROCE40.35%
Gross Margin96.44%
Operating Margin39.43%
Net Margin35.08%
Debt/Equity0.09
Current Ratio3.55

Annual Financials (USD)

Metric20212022202320242025
Revenue$1.4B$1.6B$1.8B$2.2B$2.3B
Operating Profit$287.0M$201.0M$171.0M$605.0M$872.0M
Net Profit$231.0M$182.0M$208.0M$521.0M$783.0M
EPS$0.72$0.56$0.65$1.76$2.78
Op Margin20.0%12.5%9.3%27.9%37.6%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$2.6B$3.1B$2.9B$2.9B$2.8B
Total Liabilities$406.0M$583.0M$678.0M$703.0M$683.0M
Cash$647.0M$501.0M$263.0M$217.0M$482.0M
Borrowings$51.0M$190.0M$190.0M$191.0M$173.0M

Latest News

EXEL: Lowering target price to $61.00 Argus Research · Jul 15, 2026 Is Exelixis (EXEL) Expensive After Its Recent Rally Or Still Undervalued? Simply Wall St. · Jul 11, 2026 Exelixis (EXEL) Stock Trades At A Discount After Its 236% Run Simply Wall St. · Jul 11, 2026 3 Under-the-Radar Stocks to Buy and Hold Motley Fool · Jul 10, 2026 EXEL Stock Soars 26.8% in Three Months: Is There More Room for Growth? Zacks · Jul 9, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$401.0M$363.0M$333.0M$700.0M$884.0M
Investing Cash Flow$-107.0M$-663.0M$-190.0M$-183.0M$311.0M
Financing Cash Flow$-15.0M$1.0M$-546.0M$-629.0M$-1.0B
Net Cash Flow$343.0M$-161.0M$-240.0M$-46.0M$265.0M
Free Cash Flow$337.0M$224.0M$170.0M$634.0M$844.0M

Valuation & Return Ratios

MetricValue
PEG Ratio2.56
EV / EBITDA11.99
FCF Yield7.37%
Quick Ratio3.19
Interest Coverage
Return 1Y26.80%
Return 3Y185.02%
Return 5Y231.29%

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ALGNAlign Technology, Inc. $169.29 +1.36% 27.86 $12.12B 0.00%
BBIOBridgeBio Pharma, Inc. $85.33 +1.56% -22.41 $16.71B 0.00%
BMRN $60.00 -0.04% 41.31 $11.60B 0.00%
CAI $16.45 +2.17% 49.96 $4.65B 0.00%
HALO $81.48 -0.55% 23.58 $9.66B 0.00%

About Exelixis, Inc.

Exelixis, Inc. operates as a biotechnology firm dedicated to combating cancer, primarily focusing on the identification, advancement, and marketing of novel oncological treatments within the United States. Its portfolio of commercially available therapeutics includes CABOMETYX tablets, prescribed for individuals with advanced renal cell carcinoma who have previously undergone anti-angiogenic treatment, and COMETRIQ capsules, utilized for managing progressive and metastatic medullary thyroid cancer. Both CABOMETYX and COMETRIQ originate from cabozantinib, a compound that inhibits several tyrosine kinases such as MET, AXL, RET, and VEGF receptors. Additionally, Exelixis offers COTELLIC, an MEK inhibitor employed in combination therapies for advanced melanoma, and MINNEBRO, an orally administered, non-steroidal selective mineralocorticoid receptor blocker, approved for hypertension treatment in Japan. The company's developmental pipeline features several promising candidates, such as XL092, an oral tyrosine kinase inhibitor designed to target VEGF receptors, MET, AXL, MER, and other kinases crucial for cancer proliferation; XB002, an antibody-drug conjugate containing a human monoclonal antibody against tissue factor (TF), intended for advanced solid tumors and non-Hodgkin's lymphoma; and XL102, an orally available cyclin-dependent kinase 7 (CDK7) inhibitor being developed for advanced or metastatic solid tumors. Exelixis, Inc. maintains extensive research partnerships and licensing arrangements with numerous pharmaceutical and biotechnology entities, including Ipsen Pharma SAS, Takeda Pharmaceutical Company Ltd., F. Hoffmann-La Roche Ltd., Redwood Bioscience, Inc., R.P. Scherer Technologies, LLC, Catalent Pharma Solutions, Inc., NBE Therapeutics AG, Aurigene Discovery Technologies Limited, Iconic Therapeutics, Inc., Invenra, Inc., StemSynergy Therapeutics, Inc., Genentech, Inc., Bristol-Myers Squibb Company, and Daiichi Sankyo Company, Limited. Established in 1994, the company originally operated as Exelixis Pharmaceuticals, Inc. before rebranding to Exelixis, Inc. in February 2000. Its corporate headquarters are located in Alameda, California.

Exelixis, Inc. is led by CEO Michael Morrissey, employs 1,077 people, headquartered in Alameda, US, publicly traded since 2000.

Exelixis, Inc. (EXEL) stock trades at $55.96 with a market capitalization of $14.07B. The stock is valued at a price-to-earnings (P/E) ratio of 16.38, price-to-book of 6.01, price-to-sales of 5.23. Over the past 52 weeks the stock has ranged between $33.76 and $57.40, and currently trades 2.5% below its 52-week high.

On profitability, Exelixis, Inc. generates a return on equity (ROE) of 40.99% — well above the market average, a sign of a high-quality business, return on capital employed of 40.35%, an operating margin of 39.43%, a net profit margin of 35.08%.

Official website: www.exelixis.com

Related Healthcare Stocks

LLY Drug Manufacturers - General $1185.71 -0.52% JNJ Drug Manufacturers - General $259.24 +0.88% ABBV Drug Manufacturers - General $246.04 +0.89% UNH Medical - Healthcare Plans $407.08 +0.77% MRK Drug Manufacturers - General $128.57 +0.16% NVS Drug Manufacturers - General $158.83 -0.64% NVO Biotechnology $51.58 +1.22% TMO Medical - Diagnostics & Research $594.00 +2.41% AMGN Drug Manufacturers - General $387.64 -1.39% ABT Medical - Devices $108.03 +0.70% GILD Drug Manufacturers - General $132.73 -1.18% PFE Drug Manufacturers - General $26.74 +2.06%

Popular Stocks

Apple (AAPL)Microsoft (MSFT)NVIDIA (NVDA)Alphabet (GOOGL)Amazon (AMZN)Meta (META)Tesla (TSLA)Broadcom (AVGO)JPMorgan (JPM)Visa (V)

Screens featuring this stock

High ROE Healthcare StocksLow P/E Healthcare StocksHigh Net Margin Healthcare StocksDividend Healthcare StocksLow Debt Healthcare StocksNasdaq High ROE StocksAll stock screens
Run Stock Screener Investing Guides