NASDAQ · Biotechnology

Cytokinetics, Incorporated (CYTK) Stock

$80.62 -0.15% NASDAQ: CYTK Healthcare

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM.

Valuation

MetricValue
Price$80.62
Market Cap$10.03B
P/E Ratio-11.82
P/B Ratio-12.04
P/S Ratio94.95
EPS (TTM)$0.00
52-Week High$88.31
52-Week Low$32.89
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE139.66%
ROA-65.15%
ROCE-59.60%
Gross Margin-695.45%
Operating Margin-695.45%
Net Margin-784.02%
Debt/Equity-1.56
Current Ratio4.54

Annual Financials (USD)

Metric20212022202320242025
Revenue$70.0M$95.0M$8.0M$18.0M$88.0M
Operating Profit$-186.0M$-324.0M$-496.0M$-536.0M$-612.0M
Net Profit$-215.0M$-389.0M$-526.0M$-590.0M$-785.0M
EPS$-2.80$-4.33$-5.45$-5.26$-6.54
Op Margin-264.5%-342.8%-6589.7%-2902.7%-695.4%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$841.0M$1.0B$824.0M$1.4B$1.4B
Total Liabilities$597.0M$1.1B$1.2B$1.5B$2.1B
Cash$113.0M$66.0M$113.0M$95.0M$123.0M
Borrowings$270.0M$750.0M$756.0M$789.0M$1.3B

Latest News

All You Need to Know About Cytokinetics (CYTK) Rating Upgrade to Buy Zacks · Jul 15, 2026 Wall Street Analysts Think Cytokinetics (CYTK) Could Surge 30.54%: Read This Before Placing a Bet Zacks · Jul 15, 2026 CYTK: Lowering target price to $86.00 Argus Research · Jul 15, 2026 What This Cytokinetics Insider Sale Might Mean With the Stock Up 110% Motley Fool · Jul 14, 2026 Cytokinetics Insider Sold Shares Worth $615,150, According to a Recent SEC Filing MT Newswires · Jul 14, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-143.0M$-300.0M$-414.0M$-396.0M$-510.0M
Investing Cash Flow$-197.0M$-273.0M$238.0M$-557.0M$-8.0M
Financing Cash Flow$8.0M$164.0M$58.0M$233.0M$-2.0M
Net Cash Flow$30.0M$-45.0M$46.0M$-18.0M$30.0M
Free Cash Flow$-191.0M$-311.0M$-416.0M$-400.0M$-535.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.44
EV / EBITDA-15.23
FCF Yield-5.33%
Quick Ratio4.54
Interest Coverage-5.88
Return 1Y119.45%
Return 3Y147.89%
Return 5Y169.47%

Ownership

Insiders Held0.67%
Institutions Held118.82%
Institutions Float Held119.62%
Institutional HolderSharesReport Date
T. Rowe Price Investment Management, Inc.17,523,8402026-03-31
Blackrock Inc.16,548,0112026-03-31
FMR, LLC10,723,1402026-03-31
Wellington Management Group, LLP8,009,4892026-03-31
Vanguard Portfolio Management LLC5,843,7822026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ABVXAbivax S.A. $136.94 +1.50% -24.37 $10.06B 0.00%
AXSM $238.37 -1.09% 38.05 $12.27B 0.00%
CORT $91.12 -4.45% 146.17 $9.78B 0.00%
CRSP $46.73 +0.41% -12.98 $4.51B 0.00%
HALO $81.48 -0.55% 23.58 $9.66B 0.00%

About Cytokinetics, Incorporated

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California.

Cytokinetics, Incorporated is led by CEO Robert I. Blum, employs 673 people, headquartered in South San Francisco, US, publicly traded since 2004.

Cytokinetics, Incorporated (CYTK) stock trades at $80.62 with a market capitalization of $10.03B. The stock is valued at a price-to-earnings (P/E) ratio of -11.82, price-to-book of -12.04, price-to-sales of 94.95. Over the past 52 weeks the stock has ranged between $32.89 and $88.31, and currently trades 8.7% below its 52-week high.

On profitability, Cytokinetics, Incorporated generates a return on equity (ROE) of 139.66% — well above the market average, a sign of a high-quality business, return on capital employed of -59.60%, an operating margin of -695.45%, a net profit margin of -784.02%.

Official website: www.cytokinetics.com

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