NASDAQ · Biotechnology

Clene Inc. (CLNN) Stock

$3.87 -0.26% NASDAQ: CLNN Healthcare

Valuation

MetricValue
Price$3.87
Market Cap$49.45M
P/E Ratio-1.10
P/B Ratio-1.96
P/S Ratio254.27
EPS (TTM)$0.00
52-Week High$13.50
52-Week Low$3.25
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE214.97%
ROA-171.51%
ROCE-111.61%
Gross Margin0.00%
Operating Margin0.00%
Net Margin-250.10%
Debt/Equity-0.90
Current Ratio0.82

Annual Financials (USD)

Metric20212022202320242025
Revenue$1.0M$0$1.0M$0$0
Operating Profit$-50.0M$-48.0M$-41.0M$-33.0M$-23.0M
Net Profit$-10.0M$-30.0M$-50.0M$-39.0M$-26.0M
EPS$-3.16$-4.69$-9.43$-5.67$-2.65
Op Margin-6912.6%-10234.5%-6198.8%-9676.3%-11541.5%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$63.0M$44.0M$52.0M$27.0M$18.0M
Total Liabilities$50.0M$41.0M$39.0M$36.0M$36.0M
Cash$50.0M$18.0M$29.0M$12.0M$5.0M
Borrowings$24.0M$32.0M$32.0M$21.0M$22.0M

Latest News

Top Premarket Decliners MT Newswires · Jun 22, 2026 Are Medical Stocks Lagging C4 Therapeutics (CCCC) This Year? Zacks · Jun 18, 2026 Clene (CLNN) May Find a Bottom Soon, Here's Why You Should Buy the Stock Now Zacks · Jun 4, 2026 3 Parkinson's Biotech Stocks Analysts Think Are Wildly Mispriced Simply Wall St. · May 22, 2026 Are Medical Stocks Lagging BrightSpring Health Services, Inc. (BTSG) This Year? Zacks · May 19, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-35.0M$-39.0M$-30.0M$-21.0M$-19.0M
Investing Cash Flow$-3.0M$-15.0M$-2.0M$6.0M$0
Financing Cash Flow$-2.0M$0$0$0$0
Net Cash Flow$-9.0M$-32.0M$10.0M$-17.0M$-7.0M
Free Cash Flow$-36.0M$-44.0M$-31.0M$-21.0M$-19.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.54
EV / EBITDA-2.26
FCF Yield-31.87%
Quick Ratio3.07
Interest Coverage-7.05
Return 1Y66.22%
Return 3Y-61.56%
Return 5Y-96.54%

Ownership

Insiders Held17.06%
Institutions Held20.44%
Institutions Float Held24.64%
Institutional HolderSharesReport Date
Boxer Capital Management, LLC477,5152026-03-31
SymBiosis Capital Partners, LLC431,0942026-03-31
Vanguard Capital Management LLC308,2302026-03-31
Scoggin Management, LP300,0002026-03-31
Ensign Peak Advisors, Inc257,8722026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
CNTBConnect Biopharma Holdings Limited $0.93 +5.08% -1.05 $58.27M 0.00%
CNTXContext Therapeutics Inc. $0.30 +1.10% -0.64 $27.78M 0.00%
COYACoya Therapeutics, Inc. $4.97 -0.50% -4.53 $116.46M 0.00%
MGNXMacroGenics, Inc. $3.73 +4.93% -16.25 $236.77M 0.00%
ORMPOramed Pharmaceuticals Inc. $4.25 +1.19% 1.06 $173.94M 22.27%

About Clene Inc.

Clene Inc. is led by CEO Robert Etherington, employs 75 people, headquartered in US, publicly traded since 2018.

Clene Inc. (CLNN) stock trades at $3.87 with a market capitalization of $49.45M. The stock is valued at a price-to-earnings (P/E) ratio of -1.10, price-to-book of -1.96, price-to-sales of 254.27. Over the past 52 weeks the stock has ranged between $3.25 and $13.50, and currently trades 71.3% below its 52-week high.

On profitability, Clene Inc. generates a return on equity (ROE) of 214.97% — well above the market average, a sign of a high-quality business, return on capital employed of -111.61%, an operating margin of 0.00%, a net profit margin of -250.10%.

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