NASDAQ · Biotechnology

Axsome Therapeutics, Inc. (AXSM) Stock

$168.35 -1.02% NASDAQ: AXSM Healthcare

Valuation

MetricValue
Price$168.35
Market Cap$8.66B
P/E Ratio-49.17
P/B Ratio113.99
P/S Ratio12.22
EPS (TTM)$-3.68
52-Week High$260.19
52-Week Low$117.30
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-255.60%
ROA-25.17%
ROCE-62.64%
Gross Margin92.60%
Operating Margin-24.80%
Net Margin-24.68%
Debt/Equity2.63
Current Ratio1.55

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$50.0M$271.0M$386.0M$638.0M
Operating Profit$-125.0M$-180.0M$-232.0M$-281.0M$-169.0M
Net Profit$-130.0M$-187.0M$-239.0M$-287.0M$-183.0M
EPS$-3.47$-4.60$-5.27$-5.99$-3.68
Op Margin—-359.3%-85.7%-72.7%-26.5%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$88.0M$331.0M$588.0M$568.0M$690.0M
Total Liabilities$72.0M$222.0M$397.0M$511.0M$602.0M
Cash$86.0M$201.0M$386.0M$315.0M$323.0M
Borrowings$50.0M$95.0M$186.0M$193.0M$241.0M

Latest News

Axsome Therapeutics Wins US FDA Review for Narcolepsy Drug Application MT Newswires · Jul 15, 2026 Axsome Therapeutics Announces FDA Acceptance of New Drug Application for AXS-12 for the Treatment of Cataplexy in Narcolepsy GlobeNewswire · Jul 15, 2026 Axsome Therapeutics to Report Second Quarter 2026 Financial Results on August 10 GlobeNewswire · Jul 14, 2026 3 Under-the-Radar Stocks to Buy and Hold Motley Fool · Jul 10, 2026 Axsome Therapeutics (AXSM) Stock Looks Pricey On Sales Yet Fair On Value Simply Wall St. · Jul 10, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-108.0M$-117.0M$-145.0M$-128.0M$-93.0M
Investing Cash Flow$-1.0M$-54.0M$-1.0M$-1.0M$-1.0M
Financing Cash Flow$4.0M$-4.0M$-13.0M$18.0M$-17.0M
Net Cash Flow$-97.0M$114.0M$185.0M$-71.0M$8.0M
Free Cash Flow$-109.0M$-117.0M$-146.0M$-129.0M$-94.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-1.73
EV / EBITDA-52.22
FCF Yield-0.75%
Quick Ratio1.34
Interest Coverage-37.58
Return 1Y45.36%
Return 3Y154.14%
Return 5Y449.28%

Ownership

Insiders Held15.35%
Institutions Held75.72%
Institutions Float Held89.45%
Institutional HolderSharesReport Date
Blackrock Inc.3,912,8442026-03-31
Vanguard Portfolio Management LLC2,058,1702026-03-31
Vanguard Capital Management LLC1,937,7522026-03-31
FMR, LLC1,566,9952026-03-31
Price (T.Rowe) Associates Inc1,317,0592026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $336.64 -1.11% 38.93 $4.94T 0.32%
MSFTMicrosoft Corporation $535.07 +2.38% 28.68 $3.97T 0.76%
GOOGLAlphabet Inc. $351.66 +0.97% 16.94 $4.26T 0.26%
AMZNAmazon.com, Inc. $262.43 +3.29% 19.82 $2.82T 0.00%
METAMeta Platforms, Inc. $718.67 -0.31% 27.93 $1.83T 0.28%

About Axsome Therapeutics, Inc.

Axsome Therapeutics, Inc. is led by CEO Herriot Tabuteau, employs 1,220 people, headquartered in New York City, US, publicly traded since 2015.

Axsome Therapeutics, Inc. (AXSM) stock trades at $168.35 with a market capitalization of $8.66B. The stock is valued at a price-to-earnings (P/E) ratio of -49.17, price-to-book of 113.99, price-to-sales of 12.22. Over the past 52 weeks the stock has ranged between $117.30 and $260.19, and currently trades 35.3% below its 52-week high.

On profitability, Axsome Therapeutics, Inc. generates a return on equity (ROE) of -255.60%, return on capital employed of -62.64%, an operating margin of -24.80%, a net profit margin of -24.68%.

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