OTC · Drug Manufacturers - General

Astellas Pharma Inc. (ALPMF) Stock

$12.85 +0.00% OTC: ALPMF Healthcare

Astellas Pharma Inc. operates as a global pharmaceutical enterprise, encompassing the development, manufacturing, distribution, and commercialization of medicinal products across international markets.

Valuation

MetricValue
Price$12.85
Market Cap$23.02B
P/E Ratio13.19
P/B Ratio2.11
P/S Ratio1.80
EPS (TTM)$0.97
52-Week High$17.85
52-Week Low$9.34
Dividend Yield3.81%

Financials & Margins

MetricValue
ROE17.44%
ROA8.17%
ROCE17.24%
Gross Margin76.08%
Operating Margin18.92%
Net Margin13.63%
Debt/Equity0.31
Current Ratio1.17

Annual Financials (USD)

Metric20222023202420252026
Revenue$1.30T$1.52T$1.60T$1.91T$2.15T
Operating Profit$220.0B$133.0B$25.5B$41.0B$422.3B
Net Profit$124.1B$98.7B$17.0B$50.7B$293.4B
EPS$67.05$54.09$9.47$28.24$162.98
Op Margin17.0%8.8%1.6%2.1%19.6%

Balance Sheet (USD)

Metric20222023202420252026
Total Assets$2.33T$2.46T$3.57T$3.34T$3.59T
Total Liabilities$872.1B$948.6B$1.97T$1.83T$1.75T
Cash$316.0B$376.8B$335.7B$188.4B$283.4B
Borrowings$212.7B$200.0B$1.01T$831.4B$569.5B

Latest News

Pfizer (PFE) Announces FDA Approval of PADCEV plus Keytruda in MIBC Insider Monkey · Jul 15, 2026 Pfizer Poised for Mixed Second Quarter, RBC Says MT Newswires · Jul 10, 2026 U.S. FDA Approves PADCEV® plus Keytruda® as Neoadjuvant and Adjuvant Treatment for Muscle-Invasive Bladder Cancer Regardless of Cisplatin Eligibility Business Wire · Jul 10, 2026 Sangamo holds a bankruptcy sale; VCs back a China-linked Beam competitor BioPharma Dive · Jun 24, 2026 Sector Update: Healthcare Stocks Advance in Afternoon Trading MT Newswires · Jun 23, 2026

Cash Flow (USD)

Metric20222023202420252026
Operating Cash Flow$257.4B$327.8B$172.5B$194.5B$569.8B
Investing Cash Flow$-138.9B$-173.0B$-928.3B$-146.7B$-131.3B
Financing Cash Flow$-71.1B$-80.3B$-40.5B$-43.9B$-1.3B
Net Cash Flow$-10.1B$60.9B$-41.2B$-147.3B$82.7B
Free Cash Flow$181.0B$239.2B$90.0B$137.2B$511.7B

Valuation & Return Ratios

MetricValue
PEG Ratio0.03
EV / EBITDA6.96
FCF Yield13.22%
Quick Ratio0.90
Interest Coverage28.77
Return 1Y43.05%
Return 3Y-2.45%
Return 5Y-11.91%

Ownership

Insiders Held1.34%
Institutions Held60.84%
Institutions Float Held61.67%
Institutional HolderSharesReport Date
Pacer Advisors, Inc.2,142,1282026-03-31
Paradigm Asset Management Company, LLC5,1002026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
BMXXYbioMérieux S.A. $7.60 -5.35% 21.32 $8.96B 1.45%
CHJTFCSPC Pharmaceutical Group Limited $0.98 +0.00% 21.72 $11.18B 4.08%
CSPCYCSPC Pharmaceutical Group Limited $4.04 +0.00% 21.72 $11.64B 3.71%
FMCQFFresenius Medical Care AG $44.59 +0.00% 12.84 $11.98B 3.88%
GIKLYGrifols, S.A. $5.10 +0.00% 14.79 $13.40B 0.98%

About Astellas Pharma Inc.

Astellas Pharma Inc. operates as a global pharmaceutical enterprise, encompassing the development, manufacturing, distribution, and commercialization of medicinal products across international markets. Its diverse portfolio features prominent therapies such as XTANDI, an androgen receptor signaling inhibitor for prostate cancer, and XOSPATA, an FLT3 inhibitor targeting relapsed or refractory acute myeloid leukemia in adult patients with a specific FLT3 mutation. Other key offerings include PADCEV, designed for locally advanced or metastatic urothelial cancer, and the Betanis/Myrbetriq/BETMIGA family of beta-3 adrenergic receptor agonists used to alleviate symptoms of overactive bladder, including urgency, frequent urination, and urge incontinence. The company also markets Evrenzo, an oral medication for anemia linked to chronic kidney disease, and the immunosuppressants Prograf and Advagraf/Graceptor/ASTAGRAF, critical for preventing organ rejection post-transplantation. Further contributions to its product range include mirabegron for neurogenic detrusor overactivity in children, Vesicare for general overactive bladder treatment, Eligard for prostate cancer, Harnal/Omnic for benign prostatic hyperplasia, and the antifungal agent Funguard/MYCAMINE. Astellas is actively engaged in numerous strategic alliances and collaborations to advance its research and development initiatives. These include clinical trial partnerships with Merck & Co., Inc. and CytomX Therapeutics, Inc., as well as an agreement with BANDAI NAMCO Entertainment Inc. for a smartphone-based exercise support application. The company maintains a strategic research alliance with Harvard University, focusing on the co-development of novel therapeutics and technologies. Additionally, it has a research collaboration with Actinium Pharmaceuticals, Inc. to develop targeted radiotherapies utilizing Actinium's Antibody Warhead Enabling technology platform, and an agreement with Zenith Epigenetics Ltd. to assess ZEN-3694. A collaboration agreement is also in place with Cytokinetics, Incorporated. Furthermore, Astellas has a strategic collaboration and licensing deal with Minovia Therapeutics Ltd. aimed at the research, development, and commercialization of cell therapy programs addressing diseases stemming from mitochondrial dysfunction. Established in 1923, Astellas Pharma Inc. has its corporate headquarters situated in Tokyo, Japan.

Astellas Pharma Inc. is headquartered in JP.

Astellas Pharma Inc. (ALPMF) stock trades at $12.85 with a market capitalization of $23.02B. The stock is valued at a price-to-earnings (P/E) ratio of 13.19, price-to-book of 2.11, price-to-sales of 1.80. Over the past 52 weeks the stock has ranged between $9.34 and $17.85, and currently trades 28.0% below its 52-week high. It pays a dividend yielding 3.81%.

On profitability, Astellas Pharma Inc. generates a return on equity (ROE) of 17.44%, above the typical market average, return on capital employed of 17.24%, an operating margin of 18.92%, a net profit margin of 13.63%.

In its most recent fiscal year, Astellas Pharma Inc. reported annual revenue of $2.15T, net profit of $293.4B, revenue has compounded at 11.5% a year over the last five years, profit at 19.5% a year. Profit growing faster than revenue points to expanding margins.

The balance sheet shows a debt-to-equity ratio of 0.31 — a conservative balance sheet with little leverage risk, a current ratio of 1.17, total assets of $3.59T, $283.4B in cash and equivalents.

ALPMF has an average daily trading volume of 4,008 shares, a beta of 0.08 (less volatile than the overall market).

Official website: www.astellas.com

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