NCM · Biotechnology

SNTI (SNTI) Stock

$0.37 -7.48% NCM: SNTI Healthcare

Valuation

MetricValue
Price$0.37
Market Cap$11.63M
P/E Ratio-0.35
P/B Ratio4.78
P/S Ratio1136.00
EPS (TTM)$-2.73
52-Week High$2.88
52-Week Low$0.37
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-1016.67%
ROA-119.61%
ROCE-1280.00%
Gross Margin-106.68%
Operating Margin-2361.18%
Net Margin-2343.05%
Debt/Equity7.46
Current Ratio1.64

Annual Financials (USD)

Metric20212022202320242025
Revenue$2.0M$3.0M$2.0M$0$0
Operating Profit$-40.0M$-62.0M$-93.0M$-61.0M$-64.0M
Net Profit$-55.0M$-58.0M$-71.0M$-53.0M$-61.0M
EPS$-12.67$-13.25$-20.94$-11.49$-2.73
Op Margin-1765.4%-1889.3%-4687.9%—-289668.2%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$97.0M$181.0M$119.0M$98.0M$51.0M
Total Liabilities$36.0M$54.0M$53.0M$72.0M$46.0M
Cash$56.0M$58.0M$36.0M$48.0M$16.0M
Borrowings$23.0M$37.0M$38.0M$34.0M$29.0M

Latest News

Senti Biosciences Holdings, Inc. Announces a Strategic Transaction to Unlock Value for its Gene-Circuit-Enabled Pipeline, Including SENTI-202, and to Sharpen its Focus on Next-Generation Controllable Genetic Medicines Powered by its Regulator Dial™ Technology Platform GlobeNewswire · Jul 15, 2026 Senti Biosciences Holdings Reports First Quarter 2026 Financial Results and Highlights Advancement of SENTI-202 Program into Pivotal Phase GlobeNewswire · May 14, 2026 Senti Biosciences Holdings Announces Positive FDA RMAT Meeting on Registrational Clinical and CMC Strategy for SENTI-202 in Relapsed/Refractory AML, Along with Important Efficacy and Durability Updates on the SENTI-202 Clinical Program GlobeNewswire · May 14, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-35.0M$-35.0M$-52.0M$-41.0M$-43.0M
Investing Cash Flow$-11.0M$-123.0M$18.0M$0$0
Financing Cash Flow$1.0M$113.0M$0$5.0M$3.0M
Net Cash Flow$28.0M$2.0M$-22.0M$12.0M$-32.0M
Free Cash Flow$-40.0M$-76.0M$-64.0M$-41.0M$-44.0M

Valuation & Return Ratios

MetricValue
PEG Ratio—
EV / EBITDA—
FCF Yield-148.33%
Quick Ratio1.04
Interest Coverage—
Return 1Y-68.97%
Return 3Y-91.67%
Return 5Y-99.41%

Ownership

Insiders Held47.91%
Institutions Held18.53%
Institutions Float Held35.58%
Institutional HolderSharesReport Date
NEA Management Company, LLC3,775,6152025-12-31
Nantahala Capital Management, LLC888,0002025-12-31
Vanguard Group Inc628,6972025-12-31
Geode Capital Management, LLC144,7972025-12-31
Virtu Financial LLC44,4092025-12-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ALGS $4.28 -1.04% -2.29 $26.45M 0.00%
BRNSBarinthus Biotherapeutics plc $0.67 +4.69% -0.41 — 0.00%
COEPCoeptis Therapeutics Holdings, Inc. $10.99 -8.57% -4.45 $38.62M 0.00%
CUE $32.57 +1.40% -4.05 $85.59M 0.00%
CVM $1.18 +0.00% -0.23 $8.11M 0.00%

About SNTI

SNTI is led by CEO Timothy K. Lu, publicly traded since 2021.

SNTI stock trades at $0.37 with a market capitalization of $11.63M. The stock is valued at a price-to-earnings (P/E) ratio of -0.35, price-to-book of 4.78, price-to-sales of 1136.00. Over the past 52 weeks the stock has ranged between $0.37 and $2.88, and currently trades 87.2% below its 52-week high.

On profitability, SNTI generates a return on equity (ROE) of -1016.67%, return on capital employed of -1280.00%, an operating margin of -2361.18%, a net profit margin of -2343.05%.

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