NGM · Biotechnology

PTGX (PTGX) Stock

$137.32 +1.11% NGM: PTGX Healthcare

Valuation

MetricValue
Price$137.32
Market Cap$8.83B
P/E Ratio-267.96
P/B Ratio9.79
P/S Ratio86.79
EPS (TTM)$-1.81
52-Week High$140.85
52-Week Low$43.20
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-17.06%
ROA-12.37%
ROCE-25.72%
Gross Margin100.00%
Operating Margin-6.47%
Net Margin-1.55%
Debt/Equity0.01
Current Ratio17.76

Annual Financials (USD)

Metric20212022202320242025
Revenue$27.0M$27.0M$60.0M$434.0M$46.0M
Operating Profit$-126.0M$-131.0M$-94.0M$253.0M$-158.0M
Net Profit$-126.0M$-127.0M$-79.0M$275.0M$-130.0M
EPS$-2.65$-2.52$-1.39$4.23$-2.05
Op Margin-460.0%-494.2%-156.1%58.2%-343.6%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$348.0M$248.0M$358.0M$745.0M$670.0M
Total Liabilities$48.0M$32.0M$21.0M$69.0M$55.0M
Cash$124.0M$126.0M$187.0M$97.0M$128.0M
Borrowings$6.0M$4.0M$1.0M$11.0M$10.0M

Latest News

Protagonist Therapeutics (PTGX) Stock Still Looks Stretched After FDA Priority Review Simply Wall St. · Jul 9, 2026 Protagonist Therapeutics (PTGX) After Icotyde Launch And Rusfertide Review Looks Undervalued Simply Wall St. · Jul 9, 2026 New Strong Buy Stocks for July 9th Zacks · Jul 9, 2026 Protagonist Therapeutics (PTGX) Is Up 12.5% After Rusfertide Priority Review Focus - Has The Bull Case Changed? Simply Wall St. · Jul 8, 2026 Protagonist Therapeutics (PTGX) Surges 7.1%: Is This an Indication of Further Gains? Zacks · Jul 8, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-108.0M$-108.0M$-70.0M$184.0M$58.0M
Investing Cash Flow$-17.0M$91.0M$-40.0M$-301.0M$-51.0M
Financing Cash Flow$6.0M$4.0M$38.0M$-1.0M$0
Net Cash Flow$6.0M$2.0M$61.0M$-89.0M$31.0M
Free Cash Flow$-109.0M$-109.0M$-71.0M$183.0M$56.0M

Valuation & Return Ratios

MetricValue
PEG Ratio—
EV / EBITDA-41.77
FCF Yield-1.81%
Quick Ratio17.76
Interest Coverage—
Return 1Y150.47%
Return 3Y591.55%
Return 5Y195.41%

Ownership

Insiders Held0.71%
Institutions Held125.34%
Institutions Float Held126.24%
Institutional HolderSharesReport Date
Blackrock Inc.9,779,3692026-03-31
Farallon Capital Management LLC6,348,9062026-03-31
UBS Group AG5,177,7962026-03-31
RTW Investments LP5,059,0532026-03-31
Wellington Management Group, LLP3,599,6442026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ACLXArcellx, Inc. $115.07 +0.02% -28.27 $6.73B 0.00%
AKROAkero Therapeutics, Inc. $54.65 +0.00% -19.87 $4.50B 0.00%
ALKS $50.71 -3.84% 25.87 $8.45B 0.00%
CRNX $83.81 -0.09% -8.57 $8.87B 0.00%
IMVT $39.24 +1.91% -11.09 $8.06B 0.00%

About PTGX

PTGX is led by CEO Dinesh V. Patel, employs 132 people, headquartered in Newark, US, publicly traded since 2016.

PTGX stock trades at $137.32 with a market capitalization of $8.83B. The stock is valued at a price-to-earnings (P/E) ratio of -267.96, price-to-book of 9.79, price-to-sales of 86.79. Over the past 52 weeks the stock has ranged between $43.20 and $140.85, and currently trades 2.5% below its 52-week high.

On profitability, PTGX generates a return on equity (ROE) of -17.06%, return on capital employed of -25.72%, an operating margin of -6.47%, a net profit margin of -1.55%.

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