NASDAQ · Biotechnology

BioNTech SE (BNTX) Stock

$90.07 -1.55% NASDAQ: BNTX Healthcare

BioNTech SE, a biotechnology firm, specializes in the creation and marketing of immune-based treatments for malignancies and various infectious diseases. A significant part of its oncology pipeline includes the FixVac cancer vaccine program, which features several candidates in different phases of clinical development: BNT111 is in Phase 2 for advanced melanoma.

Valuation

MetricValue
Price$90.07
Market Cap$22.78B
P/E Ratio-15.45
P/B Ratio1.06
P/S Ratio7.05
EPS (TTM)$-4.51
52-Week High$124.00
52-Week Low$79.52
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-6.67%
ROA-5.93%
ROCE-7.54%
Gross Margin77.60%
Operating Margin-52.06%
Net Margin-44.67%
Debt/Equity0.02
Current Ratio8.80

Annual Financials (USD)

Metric20212022202320242025
Revenue$19.0B$17.3B$3.8B$2.8B$2.8B
Operating Profit$15.3B$12.6B$690.0M$-1.3B$-624.0M
Net Profit$10.3B$9.4B$930.0M$-665.0M$-1.1B
EPS$41.21$37.09$3.83$-2.77$-4.51
Op Margin80.5%73.0%18.1%-47.8%-22.6%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$15.8B$23.3B$23.0B$22.5B$22.0B
Total Liabilities$3.9B$3.2B$2.8B$3.1B$2.8B
Cash$1.7B$13.9B$11.7B$9.8B$7.7B
Borrowings$302.0M$212.0M$219.0M$254.0M$267.0M

Latest News

Is BioNTech (BNTX) Undervalued As It Exits German Manufacturing Sites? Simply Wall St. · Jul 10, 2026 BioNTech (BNTX) Stock Could Be Overvalued After a 58% Five Year Slump Simply Wall St. · Jul 10, 2026 Biopharma Sector Seen Shifting to Fundamentals From Macro in H2, Morgan Stanley Says MT Newswires · Jul 8, 2026 Former Pfizer Building Is Crumbling—Just as the Stock Has Barrons.com · Jul 7, 2026 European Equities Traded in the US as American Depositary Receipts Rise in Monday Trading MT Newswires · Jul 6, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$890.0M$13.6B$5.4B$208.0M$438.0M
Investing Cash Flow$-720.0M$-399.0M$-7.7B$-2.5B$-2.5B
Financing Cash Flow$0$-986.0M$-738.0M$0$-40.0M
Net Cash Flow$483.0M$12.2B$-2.2B$-1.9B$-931.0M
Free Cash Flow$736.0M$13.2B$4.7B$-245.0M$270.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.16
EV / EBITDA-14.37
FCF Yield3.45%
Quick Ratio8.74
Interest Coverage-67.92
Return 1Y-15.22%
Return 3Y-14.97%
Return 5Y-66.70%

Ownership

Insiders Held57.13%
Institutions Held20.47%
Institutions Float Held47.76%
Institutional HolderSharesReport Date
T. Rowe Price Investment Management, Inc.5,856,0732026-03-31
FMR, LLC5,709,2402026-03-31
Primecap Management Company3,793,7112026-03-31
Flossbach von Storch SE3,680,3152026-03-31
Dodge & Cox Inc.3,676,7912026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
BIIBBiogen Inc. $202.30 +0.05% 20.80 $29.87B 0.00%
DXCMDexCom, Inc. $73.51 +2.75% 26.01 $28.37B 0.00%
GMABGenmab A/S $29.00 -2.62% 21.45 $17.80B 0.00%
INCYIncyte Corporation $129.03 +8.55% 14.00 $25.78B 0.00%
NTRANatera, Inc. $258.03 -1.51% -299.78 $36.95B 0.00%

About BioNTech SE

BioNTech SE, a biotechnology firm, specializes in the creation and marketing of immune-based treatments for malignancies and various infectious diseases. A significant part of its oncology pipeline includes the FixVac cancer vaccine program, which features several candidates in different phases of clinical development: BNT111 is in Phase 2 for advanced melanoma. BNT112 has reached Phase 1/2a for prostate cancer. BNT113 is undergoing Phase 2 investigation for HPV-positive head and neck cancers. BNT114 is in Phase 1 for triple-negative breast cancer. BNT115 is also in Phase 1, targeting ovarian cancer. BNT116 is a preclinical candidate for non-small cell lung cancer. The company also pioneers personalized therapies that target neoantigens, such as Autogene cevumeran (BNT122), which is in Phase 2 for first-line melanoma and Phase 1a/1b for a range of solid tumors. Furthermore, its pipeline includes an mRNA-based intratumoral immunotherapy, SAR441000, currently in Phase 1 for solid tumors, as well as BNT141 and BNT142, also in Phase 1 for multiple solid tumors. BioNTech's portfolio extends to RiboCytokine therapies (BNT151, BNT152, and BNT153) aimed at solid tumors, and cutting-edge chimeric antigen receptor T-cell (CAR T-cell) immunotherapies like BNT211 for various solid tumors and BNT221 for other types of cancer. Immune checkpoint modulators, specifically GEN1046 and GEN1042, are also under Phase 1/2 clinical investigation for solid tumors. Beyond these, the firm is developing BNT321, an IgG1 monoclonal antibody in Phase 2 for pancreatic cancer, and BNT411, a small molecule immunomodulator candidate for solid tumors. Its broader scope encompasses preventative vaccines for illnesses like COVID-19 and Influenza, additional immunotherapies for infectious diseases, and protein replacement therapies designed for rare conditions. To advance its extensive pipeline, BioNTech has forged strategic partnerships with major pharmaceutical and biotechnology firms, including Genentech, Sanofi S.A., Genmab A/S, Pfizer Inc., Shanghai Fosun Pharmaceutical (Group) Co., Ltd., and Regeneron Pharmaceuticals, Inc. Established in 2008, BioNTech SE maintains its principal operations in Mainz, Germany.

BioNTech SE is headquartered in DE.

BioNTech SE (BNTX) stock trades at $90.07 with a market capitalization of $22.78B. The stock is valued at a price-to-earnings (P/E) ratio of -15.45, price-to-book of 1.06, price-to-sales of 7.05. Over the past 52 weeks the stock has ranged between $79.52 and $124.00, and currently trades 27.4% below its 52-week high.

On profitability, BioNTech SE generates a return on equity (ROE) of -6.67%, return on capital employed of -7.54%, an operating margin of -52.06%, a net profit margin of -44.67%.

In its most recent fiscal year, BioNTech SE reported annual revenue of $2.8B, net profit of $-1.1B, revenue has compounded at 41.7% a year over the last five years.

The balance sheet shows a debt-to-equity ratio of 0.02 — a conservative balance sheet with little leverage risk, a current ratio of 8.80, total assets of $22.0B, $7.7B in cash and equivalents.

BNTX has an average daily trading volume of 958,473 shares, a beta of 1.32 (more volatile than the overall market).

Official website: www.biontech.de

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